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Cancer Research related Peptides
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Etc. > Peptide

Cancer Research related Peptides

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ANASPEC
개요
Cancer 연구를 위한 Purity: ≥95% by HPLC의 고순도 펩타이드

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주문정보

Cat No. 품명 규격 제조사 제품정보 수량 견적문의
AS-61456 [Asp370] - Tyrosinase (368 - 376) 1 mg Anaspec This tumor antigenic peptide presented by HLA-A2 antigen to CTLs, is a tyrosinase fragment. Tyrosinase is a membrane-bound protein involved in the melanin synthesis pathway that is expressed by virtually all primary melanoma lesions and by most of metastatic lesions. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-64798 AH1 Sequence (6 - 14) 1 mg Anaspec This AH1 sequence (amino acids 6 to 14) is the H2-Ld-restricted epitope derived from gp-70 (endogenous retroviral gene product envelope glycoprotein 70), which is expressed in CT26 (colon carcinoma cells) and numerous other tumor cell lines. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61616 Bak BH3 1 mg Anaspec This peptide, derived from the BH3 domain of Bak (Flu-BakBH3), has been shown to have high-affinity binding to a surface pocket of the Bcl-XL protein that is essential for its death antagonist function. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-64590 Bak BH3 peptide, TAMRA - labeled 1 mg Anaspec This peptide is derived from the BH3 domain of Bak (Flu-BakBH3). It has high-affinity binding to a surface pocket of the Bcl-XL protein that is essential for its death antagonist function. This peptide is labeled with 5-TAMRA on the N-terminus, Abs/Em= 541/568 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-62266 Bax BH3 peptide (55 - 74), wild type 1 mg Anaspec This is a 20–amino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models. In addition to disrupting Bax/Bcl-2 and Bax/Bcl-XL, it can promote cytochrome c release from isolated mitochondria. Bax BH3 belongs to the Bcl-2 protein family which consists of both pro-apoptotic and anti-apoptotic members. Bax BH3 acts to regulate apoptosis via governance of the 'intrinsic' pathway of cell death. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-64082 Bcl - 2 Binding Peptide, Bad BH3 Peptide 1 mg Anaspec This is a bcl-2 binding peptide. This peptide is derived from the BH3 domain (a death domain) of Bad, amino acid residues 140 to 165. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61711 Bid BH3 Peptide 1 mg Anaspec BID is a pro-apoptotic member of the 'BH3-only' (BOPS) subset of the BCL-2 family of proteins that constitute a critical control point in apoptosis. Bid is the first of the BOPs reported to bind and activate Bcl-2, Bax, and Bak. Bid serves as a death-inducing ligand that moves from the cytosol to the mitochondrial membrane to inactivate Bcl-2 or to activate Bax. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61712 Bid BH3, FAM labeled 1 mg Anaspec This is a 5-FAM-labeled Bid BH3 peptide. Bid is a pro-apoptotic member of the 'BH3-only' subset of the BCL-2 family proteins that constitute a critical control point in apoptosis. Bid interconnects extrinsic pathway TNFR1 and Fas death signals to the mitochondrial amplification of the intrinsic pathway. The references listed below belong to the unlabeled Bid BH3. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-62278 Bim BH3, Peptide III 1 mg Anaspec This Bim peptide belongs to the pro-apoptotic Bcl-2 family of proteins. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-62279 Bim BH3, Peptide IV 1 mg Anaspec This Bim peptide belongs to the pro-apoptotic group of the Bcl-2 family of proteins. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-24194 c - Myc peptide epitope 1 mg Anaspec c-Myc, the product of the c-myc proto-oncogene, is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription in cell proliferation, cell differentiation and apoptosis. This peptide is a human c-myc epitope. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-20590 c - Myc peptide epitope 5mg Anaspec c-Myc, the product of the c-myc proto-oncogene, is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription in cell proliferation, cell differentiation and apoptosis. This peptide is a human c-myc epitope. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-65302 Enhanced Green Fluorescent Protein, EGFP (200 - 208) 1 mg Anaspec This peptide is H2-Kd-restricted enhanced green fluorescent protein (EGFP)-derived peptide (200-208) and represents a CD8 T cell epitope. Immunization with this peptide stimulates IFNg production, thus making this peptide a model tumor antigen for the experimental development of antigen-specific vaccines against cancer. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61277 G209 - 2M, gp100 (209 - 217) 1 mg Anaspec This modified gp100 peptide amino acids 209 to 217 is a MHC-associated HLA-A2.1-restricted epitope derived from melanoma antigene. It can be processed, presented, and recognized by T cells. Alteration of the G209 peptide to G209-2M at the second amino acid changing threonine to a methionine was found to increase the affinity for MHC-associated HLA-A2.1 resulting in enhanced induction of T cells reactive to native gp100 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61515 GAD65 (206 - 220) 1 mg Anaspec A Glutamic acid decarboxylase 2 (GAD2) peptide corresponding to residues 206 to 220 of GAD65. GAD2 is presented to T cells in association with I-Ag7 MHC class II molecules. This peptide was also used as a part of Ig chimeras to test whether IL-10 interferes with expression of CTLA-4. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-62589 gp100 (25 - 33), human 1 mg Anaspec This is amino acids 25 to 33 fragment of human melanoma antigen gp100. This H-2Db restricted epitope is recognized by T cells. The gp100-specific, H-2Db-restricted, CD8+ T cells are capable of recognizing B16 melanoma but not normal melanocytes. This peptide was used as an immunogen in multiple cancer immunotherapy studies. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61528 HIF - 1 {alpha} (556 - 574) 1 mg Anaspec This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-65581 Human PD - L1 inhibitor I 1 mg Anaspec Human PD-L1 inhibitor I is a peptide-based molecule. It binds to human PD-1 and inhibits PD-1/PD-L1 binding. This peptide, PDL-1 inhibitor I has anchor residues, WDY that influence binding of hPD-L1 to hPD-1. Developing inhibitors specifically blocking the PD-1/PD-L1 pathway has become a popular approach toward cancer treatment. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-65582 Human PD - L1 inhibitor II 1 mg Anaspec Human PD-L1 inhibitor II is a peptide-based molecule. It binds to human PD-1 and inhibits PD-1/PD-L1 binding. This peptide, PDL-1 inhibitor I has anchor residues, WDY that influence binding of hPD-L1 to hPD-1. Developing inhibitors specifically blocking the PD-1/PD-L1 pathway has become a popular approach toward cancer treatment. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-65583 Human PD - L1 inhibitor III 1 mg Anaspec Human PD-L1 inhibitor III is a peptide-based molecule. It binds to human PD-1 and inhibits PD-1/PD-L1 binding. This peptide, hPDL-1 inhibitor III has anchor residues (underlined), TEKDYRHGNIRMKLAYDL that influence binding of hPD-L1 to hPD-1. Developing inhibitors specifically blocking the PD-1/PD-L1 pathway has become a popular approach toward cancer treatment. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-65584 Human PD - L1 inhibitor IV 1 mg Anaspec Human PD-L1 inhibitor IV is a peptide-based molecule. It binds to human PD-1 and inhibits PD-1/PD-L1 binding. This peptide, hPDL-1 inhibitor IV has anchor residues (underlined), GNWDYNSQRAQLYNQ that influence binding of hPD-L1 to hPD-1. Developing inhibitors specifically blocking the PD-1/PD-L1 pathway has become a popular approach toward cancer treatment. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-64684 Kisspeptin - 10 (Kp - 10), Metastin (110 - 119), amide, mouse, rat 1 mg Anaspec This amidated peptide sequence is found in C-terminal residues 110 to 119 of the neurohormone Metastin (also referred to as Kisspeptin-10). This peptide increases plasma concentrations of GH (Growth Hormone) and LH (Luteinizing Hormone) in prepubertal dai 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-64240 Kisspeptin - 10 (Kp - 10), Metastin (45 - 54) 1 mg Anaspec This peptide sequence is found in residues 45 to 54 of Metastin (also referred to as Kisspeptin-10). This peptide increases plasma concentrations of GH (Growth Hormone) and LH (Luteinizing Hormone) in prepubertal dairy heifers. This peptide is the minimal sequence needed to activate GPR54 signaling, which may function in negatively regulating CXCR4’s role in programming tumor metastasis. Specifically, Kisspeptin-10 inhibits signaling and chemotaxis induced by SDF-1. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-62169 LyP - 1, Peptide 1 1 mg Anaspec LyP-1 recognizes lymphatics and tumor cells in certain tumors, but not lymphatics in normal tissues. Screening on breast carcinoma xenografts shows positive to cyclic 9-amino-acid peptide, LyP-1. The LyP-1 also recognizes an osteosarcoma xenograft, and spontaneous prostate and breast cancers in transgenic mice. LyP-1 peptide is detected in tumor structures that are positive for several lymphatic endothelial markers and negative for blood vessel markers. LyP-1 accumulates in the nuclei of the putative lymphatic cells, and in the nuclei of tumor cells. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61355 MAGE - 3 (271 - 279) 1 mg Anaspec This is a HLA-A*0201–restricted peptide derived from melanoma antigens encoded by MAGE-3. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61451 MUC1, tandem repeat fragment 1 mg Anaspec This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61334 MUC5AC 3 1 mg Anaspec This glycopeptide is a 16-amino acid modified fragment of mucin 5/MUC5AC, where T* is a GalNac labeled threonine 3. Mucin-type linkages (GalNAc 1-O-Ser/Thr) are initiated by a family of glycosyltransferases known as the UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases (ppGaNTases). These enzymes transfer GalNAc from the sugar donor UDP-GalNAc to serine and threonine residues, forming an alpha anomeric linkage. The MUC5AC gene, which is mainly expressed in gastric and respiratory mucosae, exhibits 8 amino acid tandemly repeated domain, the consensus peptide TTSTTSAP. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61329 MUC5AC, Analog 1 1 mg Anaspec This peptide is derived from the human mucin MUC5AC gene sequence. Data suggest that MUC5A and MUC5C are part of the same gene MUC5AC, which is distinct from MUC5B. The gene MUC5AC is mainly expressed in gastric, tracheo-bronchial mucosae and some tumors, it exhibits two kinds of deduced peptide domains, one of which is 8 amino acid tandemly repeated domain, a consensus peptide TTSTTSAP. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61333 MUC5AC - 13 1 mg Anaspec This glycopeptide is an N-acetyl galactosamine (GalNAc)-modified MUC5AC mucin peptide containing the single site of threonine 13 labeled with GalNAc (T*). Polypeptide N-acetylgalactosaminyltransferase (ppGaNTase) catalyzes the transfer of GalNAc from the nucleotide sugar UDP-GalNAc to threonine. The MUC5AC gene is mainly expressed in gastric and tracheo-bronchial mucosae, and some tumors. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61332 MUC5AC - 3/13 1 mg Anaspec This glycopeptide is a MUC5AC peptide with two sites (Thr3 and Thr13) labeled with GalNAc, where the asterisk denotes GalNAc-modified residues. Mucin type O-linked glycosylation is initiated by the action of a family of UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferases (ppGaNTase), which catalyze the transfer of GalNAc from the nucleotide sugar UDP-GalNAc to the hydroxyl group of either serine or threonine. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-64087 Noxa A BH3 peptide, cell permeable 1 mg Anaspec This cell permeable peptide is derived from the BH3 domain (a death domain) of Noxa A, amino acid residues 17 to 36. Eight D-Arginine residues and a Glycine linker residue are added to the amino terminal of the peptide. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-62282 Noxa BH3, Peptide 1 1 mg Anaspec This peptide belongs to the Bcl-2 family of proteins. Noxa gene encodes a Bcl-2 homology 3 (BH3)-only member of this family; it contains the BH3 region, not other BH domains. When ectopically expressed, Noxa undergoes BH3 motif-dependent localization to mitochondria, it interacts with anti-apoptotic Bcl-2 family members resulting in the activation of caspase-9. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-65341 Nuclear Factor (Erythroid - derived 2)like 2 (74 - 87); Nrf2 (74 - 87); NFE2L2 (74 - 87) 5 mg Anaspec This peptide is derived from the Neh2 domain of nuclear factor (erythroid-derived 2)-like 2, or Nrf2. Nrf2 is a bZIP transcription factor that regulates the expression of antioxidative and cytoproptective genes. The DxETGE motif of this peptide binds Keap1 Kelch adaptor protein and displaces Nrf2 from Keap1. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-62748 Shepherdin (79 - 87) 1 mg Anaspec This is amino acids 79 to 87 fragment of shepherdin, a novel peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability. For its potent and broad antitumor activity, selectivity of action in tumor cells versus normal tissues, and inhibition of tumor growth in vivo without toxicity, shepherdin may offer a promising approach for rational cancer therapy. This sequence is also known as K79–K90. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-65371 Thrombospondin - derived Peptide; Cyclic CSVTCG 1 mg Anaspec This peptide is derived from thrombospondin and represents a binding motif responsible for thrombospondin-CD36 interaction. It is cyclized through a disulfide bond. Thrombospondin is a matrix-bound glycoprotein involved in cancer metastasis, tumor adhesion, and angiogenesis. This peptide has been shown to competitively inhibit platelet aggregation and tumor metastasis. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-61058 TRP - 2 (180 - 188) 1 mg Anaspec This peptide is derived from tyrosinase-related protein 2 (TRP2) residues 180-188. TRP2 belongs to the melanocyte differentiation antigens and has been implicated as a target for immunotherapy of human as well as murine melanoma. Studies show that this TRP2 derived peptide can bind to mouse and human MHC class I molecules. Immunization with TRP2 peptide loaded dendritic cells (DCs) results in effective induction of antitumor immunity. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-64811 TRP - 2, Tyrosinase - related Protein 2 (181 - 188) 1 mg Anaspec This peptide is derived from tyrosinase-related protein 2 (TRP2) residues 181-188, and has been identified as the primary epitope of TRP2 recognized by anti-B16 melanoma cytotoxic T lymphocytes (CTLs). 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-60628 VEGFR2/KDR Antagonist 1 mg Anaspec This peptide is a specific VEGFR2/KDR heptapeptide antagonist, it binds VEGFR2 (KDR/flk), completely inhibiting VEGF binding to KDR and preventing VEGF-induced angiogenesis in-vivo. It specifically inhibits human endothelial cell proliferation in-vitro and totally abolishes VEGF-induced angiogenesis in-vivo. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
AS-62621 WP9QY, TNF - alpha Antagonist 1 mg Anaspec This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
전체선택
[Asp370] - Tyrosinase (368 - 376)
Cat No.
AS-61456
규격
1 mg
제조사
Anaspec
제품정보
This tumor antigenic peptide presented by HLA-A2 antigen to CTLs, is a tyrosinase fragment. Tyrosinase is a membrane-bound protein involved in the melanin synthesis pathway that is expressed by virtually all primary melanoma lesions and by most of metastatic lesions.
수량
수량증가수량감소
AH1 Sequence (6 - 14)
Cat No.
AS-64798
규격
1 mg
제조사
Anaspec
제품정보
This AH1 sequence (amino acids 6 to 14) is the H2-Ld-restricted epitope derived from gp-70 (endogenous retroviral gene product envelope glycoprotein 70), which is expressed in CT26 (colon carcinoma cells) and numerous other tumor cell lines.
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수량증가수량감소
Bak BH3
Cat No.
AS-61616
규격
1 mg
제조사
Anaspec
제품정보
This peptide, derived from the BH3 domain of Bak (Flu-BakBH3), has been shown to have high-affinity binding to a surface pocket of the Bcl-XL protein that is essential for its death antagonist function.
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수량증가수량감소
Bak BH3 peptide, TAMRA - labeled
Cat No.
AS-64590
규격
1 mg
제조사
Anaspec
제품정보
This peptide is derived from the BH3 domain of Bak (Flu-BakBH3). It has high-affinity binding to a surface pocket of the Bcl-XL protein that is essential for its death antagonist function. This peptide is labeled with 5-TAMRA on the N-terminus, Abs/Em= 541/568
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수량증가수량감소
Bax BH3 peptide (55 - 74), wild type
Cat No.
AS-62266
규격
1 mg
제조사
Anaspec
제품정보
This is a 20–amino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models. In addition to disrupting Bax/Bcl-2 and Bax/Bcl-XL, it can promote cytochrome c release from isolated mitochondria. Bax BH3 belongs to the Bcl-2 protein family which consists of both pro-apoptotic and anti-apoptotic members. Bax BH3 acts to regulate apoptosis via governance of the 'intrinsic' pathway of cell death.
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수량증가수량감소
Bcl - 2 Binding Peptide, Bad BH3 Peptide
Cat No.
AS-64082
규격
1 mg
제조사
Anaspec
제품정보
This is a bcl-2 binding peptide. This peptide is derived from the BH3 domain (a death domain) of Bad, amino acid residues 140 to 165.
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수량증가수량감소
Bid BH3 Peptide
Cat No.
AS-61711
규격
1 mg
제조사
Anaspec
제품정보
BID is a pro-apoptotic member of the 'BH3-only' (BOPS) subset of the BCL-2 family of proteins that constitute a critical control point in apoptosis. Bid is the first of the BOPs reported to bind and activate Bcl-2, Bax, and Bak. Bid serves as a death-inducing ligand that moves from the cytosol to the mitochondrial membrane to inactivate Bcl-2 or to activate Bax.
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수량증가수량감소
Bid BH3, FAM labeled
Cat No.
AS-61712
규격
1 mg
제조사
Anaspec
제품정보
This is a 5-FAM-labeled Bid BH3 peptide. Bid is a pro-apoptotic member of the 'BH3-only' subset of the BCL-2 family proteins that constitute a critical control point in apoptosis. Bid interconnects extrinsic pathway TNFR1 and Fas death signals to the mitochondrial amplification of the intrinsic pathway. The references listed below belong to the unlabeled Bid BH3.
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수량증가수량감소
Bim BH3, Peptide III
Cat No.
AS-62278
규격
1 mg
제조사
Anaspec
제품정보
This Bim peptide belongs to the pro-apoptotic Bcl-2 family of proteins.
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수량증가수량감소
Bim BH3, Peptide IV
Cat No.
AS-62279
규격
1 mg
제조사
Anaspec
제품정보
This Bim peptide belongs to the pro-apoptotic group of the Bcl-2 family of proteins.
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수량증가수량감소
c - Myc peptide epitope
Cat No.
AS-24194
규격
1 mg
제조사
Anaspec
제품정보
c-Myc, the product of the c-myc proto-oncogene, is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription in cell proliferation, cell differentiation and apoptosis. This peptide is a human c-myc epitope.
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수량증가수량감소
c - Myc peptide epitope
Cat No.
AS-20590
규격
5mg
제조사
Anaspec
제품정보
c-Myc, the product of the c-myc proto-oncogene, is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription in cell proliferation, cell differentiation and apoptosis. This peptide is a human c-myc epitope.
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Enhanced Green Fluorescent Protein, EGFP (200 - 208)
Cat No.
AS-65302
규격
1 mg
제조사
Anaspec
제품정보
This peptide is H2-Kd-restricted enhanced green fluorescent protein (EGFP)-derived peptide (200-208) and represents a CD8 T cell epitope. Immunization with this peptide stimulates IFNg production, thus making this peptide a model tumor antigen for the experimental development of antigen-specific vaccines against cancer.
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G209 - 2M, gp100 (209 - 217)
Cat No.
AS-61277
규격
1 mg
제조사
Anaspec
제품정보
This modified gp100 peptide amino acids 209 to 217 is a MHC-associated HLA-A2.1-restricted epitope derived from melanoma antigene. It can be processed, presented, and recognized by T cells. Alteration of the G209 peptide to G209-2M at the second amino acid changing threonine to a methionine was found to increase the affinity for MHC-associated HLA-A2.1 resulting in enhanced induction of T cells reactive to native gp100
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GAD65 (206 - 220)
Cat No.
AS-61515
규격
1 mg
제조사
Anaspec
제품정보
A Glutamic acid decarboxylase 2 (GAD2) peptide corresponding to residues 206 to 220 of GAD65. GAD2 is presented to T cells in association with I-Ag7 MHC class II molecules. This peptide was also used as a part of Ig chimeras to test whether IL-10 interferes with expression of CTLA-4.
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gp100 (25 - 33), human
Cat No.
AS-62589
규격
1 mg
제조사
Anaspec
제품정보
This is amino acids 25 to 33 fragment of human melanoma antigen gp100. This H-2Db restricted epitope is recognized by T cells. The gp100-specific, H-2Db-restricted, CD8+ T cells are capable of recognizing B16 melanoma but not normal melanocytes. This peptide was used as an immunogen in multiple cancer immunotherapy studies.
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HIF - 1 {alpha} (556 - 574)
Cat No.
AS-61528
규격
1 mg
제조사
Anaspec
제품정보
This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process
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Human PD - L1 inhibitor I
Cat No.
AS-65581
규격
1 mg
제조사
Anaspec
제품정보
Human PD-L1 inhibitor I is a peptide-based molecule. It binds to human PD-1 and inhibits PD-1/PD-L1 binding. This peptide, PDL-1 inhibitor I has anchor residues, WDY that influence binding of hPD-L1 to hPD-1. Developing inhibitors specifically blocking the PD-1/PD-L1 pathway has become a popular approach toward cancer treatment.
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Human PD - L1 inhibitor II
Cat No.
AS-65582
규격
1 mg
제조사
Anaspec
제품정보
Human PD-L1 inhibitor II is a peptide-based molecule. It binds to human PD-1 and inhibits PD-1/PD-L1 binding. This peptide, PDL-1 inhibitor I has anchor residues, WDY that influence binding of hPD-L1 to hPD-1. Developing inhibitors specifically blocking the PD-1/PD-L1 pathway has become a popular approach toward cancer treatment.
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Human PD - L1 inhibitor III
Cat No.
AS-65583
규격
1 mg
제조사
Anaspec
제품정보
Human PD-L1 inhibitor III is a peptide-based molecule. It binds to human PD-1 and inhibits PD-1/PD-L1 binding. This peptide, hPDL-1 inhibitor III has anchor residues (underlined), TEKDYRHGNIRMKLAYDL that influence binding of hPD-L1 to hPD-1. Developing inhibitors specifically blocking the PD-1/PD-L1 pathway has become a popular approach toward cancer treatment.
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Human PD - L1 inhibitor IV
Cat No.
AS-65584
규격
1 mg
제조사
Anaspec
제품정보
Human PD-L1 inhibitor IV is a peptide-based molecule. It binds to human PD-1 and inhibits PD-1/PD-L1 binding. This peptide, hPDL-1 inhibitor IV has anchor residues (underlined), GNWDYNSQRAQLYNQ that influence binding of hPD-L1 to hPD-1. Developing inhibitors specifically blocking the PD-1/PD-L1 pathway has become a popular approach toward cancer treatment.
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Kisspeptin - 10 (Kp - 10), Metastin (110 - 119), amide, mouse, rat
Cat No.
AS-64684
규격
1 mg
제조사
Anaspec
제품정보
This amidated peptide sequence is found in C-terminal residues 110 to 119 of the neurohormone Metastin (also referred to as Kisspeptin-10). This peptide increases plasma concentrations of GH (Growth Hormone) and LH (Luteinizing Hormone) in prepubertal dai
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Kisspeptin - 10 (Kp - 10), Metastin (45 - 54)
Cat No.
AS-64240
규격
1 mg
제조사
Anaspec
제품정보
This peptide sequence is found in residues 45 to 54 of Metastin (also referred to as Kisspeptin-10). This peptide increases plasma concentrations of GH (Growth Hormone) and LH (Luteinizing Hormone) in prepubertal dairy heifers. This peptide is the minimal sequence needed to activate GPR54 signaling, which may function in negatively regulating CXCR4’s role in programming tumor metastasis. Specifically, Kisspeptin-10 inhibits signaling and chemotaxis induced by SDF-1.
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LyP - 1, Peptide 1
Cat No.
AS-62169
규격
1 mg
제조사
Anaspec
제품정보
LyP-1 recognizes lymphatics and tumor cells in certain tumors, but not lymphatics in normal tissues. Screening on breast carcinoma xenografts shows positive to cyclic 9-amino-acid peptide, LyP-1. The LyP-1 also recognizes an osteosarcoma xenograft, and spontaneous prostate and breast cancers in transgenic mice. LyP-1 peptide is detected in tumor structures that are positive for several lymphatic endothelial markers and negative for blood vessel markers. LyP-1 accumulates in the nuclei of the putative lymphatic cells, and in the nuclei of tumor cells.
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MAGE - 3 (271 - 279)
Cat No.
AS-61355
규격
1 mg
제조사
Anaspec
제품정보
This is a HLA-A*0201–restricted peptide derived from melanoma antigens encoded by MAGE-3.
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MUC1, tandem repeat fragment
Cat No.
AS-61451
규격
1 mg
제조사
Anaspec
제품정보
This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies
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MUC5AC 3
Cat No.
AS-61334
규격
1 mg
제조사
Anaspec
제품정보
This glycopeptide is a 16-amino acid modified fragment of mucin 5/MUC5AC, where T* is a GalNac labeled threonine 3. Mucin-type linkages (GalNAc 1-O-Ser/Thr) are initiated by a family of glycosyltransferases known as the UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases (ppGaNTases). These enzymes transfer GalNAc from the sugar donor UDP-GalNAc to serine and threonine residues, forming an alpha anomeric linkage. The MUC5AC gene, which is mainly expressed in gastric and respiratory mucosae, exhibits 8 amino acid tandemly repeated domain, the consensus peptide TTSTTSAP.
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MUC5AC, Analog 1
Cat No.
AS-61329
규격
1 mg
제조사
Anaspec
제품정보
This peptide is derived from the human mucin MUC5AC gene sequence. Data suggest that MUC5A and MUC5C are part of the same gene MUC5AC, which is distinct from MUC5B. The gene MUC5AC is mainly expressed in gastric, tracheo-bronchial mucosae and some tumors, it exhibits two kinds of deduced peptide domains, one of which is 8 amino acid tandemly repeated domain, a consensus peptide TTSTTSAP.
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MUC5AC - 13
Cat No.
AS-61333
규격
1 mg
제조사
Anaspec
제품정보
This glycopeptide is an N-acetyl galactosamine (GalNAc)-modified MUC5AC mucin peptide containing the single site of threonine 13 labeled with GalNAc (T*). Polypeptide N-acetylgalactosaminyltransferase (ppGaNTase) catalyzes the transfer of GalNAc from the nucleotide sugar UDP-GalNAc to threonine. The MUC5AC gene is mainly expressed in gastric and tracheo-bronchial mucosae, and some tumors.
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MUC5AC - 3/13
Cat No.
AS-61332
규격
1 mg
제조사
Anaspec
제품정보
This glycopeptide is a MUC5AC peptide with two sites (Thr3 and Thr13) labeled with GalNAc, where the asterisk denotes GalNAc-modified residues. Mucin type O-linked glycosylation is initiated by the action of a family of UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferases (ppGaNTase), which catalyze the transfer of GalNAc from the nucleotide sugar UDP-GalNAc to the hydroxyl group of either serine or threonine.
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Noxa A BH3 peptide, cell permeable
Cat No.
AS-64087
규격
1 mg
제조사
Anaspec
제품정보
This cell permeable peptide is derived from the BH3 domain (a death domain) of Noxa A, amino acid residues 17 to 36. Eight D-Arginine residues and a Glycine linker residue are added to the amino terminal of the peptide.
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Noxa BH3, Peptide 1
Cat No.
AS-62282
규격
1 mg
제조사
Anaspec
제품정보
This peptide belongs to the Bcl-2 family of proteins. Noxa gene encodes a Bcl-2 homology 3 (BH3)-only member of this family; it contains the BH3 region, not other BH domains. When ectopically expressed, Noxa undergoes BH3 motif-dependent localization to mitochondria, it interacts with anti-apoptotic Bcl-2 family members resulting in the activation of caspase-9.
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Nuclear Factor (Erythroid - derived 2)like 2 (74 - 87); Nrf2 (74 - 87); NFE2L2 (74 - 87)
Cat No.
AS-65341
규격
5 mg
제조사
Anaspec
제품정보
This peptide is derived from the Neh2 domain of nuclear factor (erythroid-derived 2)-like 2, or Nrf2. Nrf2 is a bZIP transcription factor that regulates the expression of antioxidative and cytoproptective genes. The DxETGE motif of this peptide binds Keap1 Kelch adaptor protein and displaces Nrf2 from Keap1.
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Shepherdin (79 - 87)
Cat No.
AS-62748
규격
1 mg
제조사
Anaspec
제품정보
This is amino acids 79 to 87 fragment of shepherdin, a novel peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability. For its potent and broad antitumor activity, selectivity of action in tumor cells versus normal tissues, and inhibition of tumor growth in vivo without toxicity, shepherdin may offer a promising approach for rational cancer therapy. This sequence is also known as K79–K90.
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Thrombospondin - derived Peptide; Cyclic CSVTCG
Cat No.
AS-65371
규격
1 mg
제조사
Anaspec
제품정보
This peptide is derived from thrombospondin and represents a binding motif responsible for thrombospondin-CD36 interaction. It is cyclized through a disulfide bond. Thrombospondin is a matrix-bound glycoprotein involved in cancer metastasis, tumor adhesion, and angiogenesis. This peptide has been shown to competitively inhibit platelet aggregation and tumor metastasis.
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TRP - 2 (180 - 188)
Cat No.
AS-61058
규격
1 mg
제조사
Anaspec
제품정보
This peptide is derived from tyrosinase-related protein 2 (TRP2) residues 180-188. TRP2 belongs to the melanocyte differentiation antigens and has been implicated as a target for immunotherapy of human as well as murine melanoma. Studies show that this TRP2 derived peptide can bind to mouse and human MHC class I molecules. Immunization with TRP2 peptide loaded dendritic cells (DCs) results in effective induction of antitumor immunity.
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TRP - 2, Tyrosinase - related Protein 2 (181 - 188)
Cat No.
AS-64811
규격
1 mg
제조사
Anaspec
제품정보
This peptide is derived from tyrosinase-related protein 2 (TRP2) residues 181-188, and has been identified as the primary epitope of TRP2 recognized by anti-B16 melanoma cytotoxic T lymphocytes (CTLs).
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VEGFR2/KDR Antagonist
Cat No.
AS-60628
규격
1 mg
제조사
Anaspec
제품정보
This peptide is a specific VEGFR2/KDR heptapeptide antagonist, it binds VEGFR2 (KDR/flk), completely inhibiting VEGF binding to KDR and preventing VEGF-induced angiogenesis in-vivo. It specifically inhibits human endothelial cell proliferation in-vitro and totally abolishes VEGF-induced angiogenesis in-vivo.
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WP9QY, TNF - alpha Antagonist
Cat No.
AS-62621
규격
1 mg
제조사
Anaspec
제품정보
This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.
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관련제품

Cat No. 품명 규격 제조사 제품정보 수량 견적문의
ANA-AS-71120 SensoLyte® AMC Caspase Profiling Kit *Fluorimetric* 1 kit Anaspec The SensoLyte® Caspase Profiling Kit contains a series of AMC-based peptide substrates as fluorogenic indicators for assaying caspase protease activities. The kit contains a well-designed plate in which a series of AMC-based caspase substrates are coated with both positive and negative controls. It provides the best solution for profiling caspases or caspase inhibitors. *384-well plate format is available on custom basis. Kit Size: 2 plates 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
ANA-AS-71118 SensoLyte® Homogeneous AMC Caspase-3/7 Assay Kit 1 kit Anaspec The SensoLyte® Homogeneous AMC Capase-3/7 Assay Kit uses Ac-DEVD-AMC as the fluorogenic indicator for assaying caspase-3/7 activities. Upon caspase-3/7 cleavage, Ac-DEVD-AMC generates the AMC fluorophore which has bright blue fluorescence and can be detected at Ex/Em=354 nm/442 nm. A bi-function assay buffer in this kit is designed to lyze the cells and measure the enzyme activity at the same time. Thus, this kit can measure caspase-3/7 activity in cell culture directly in a 96-well or 384-well plate without a time-consuming cell extraction step. In case the cells are cultured in larger plates or flasks, a lysis buffer and protocol for cell lysate preparation are also conveniently included in the kit. The kit is suitable for high throughput screening of apoptosis inducers and inhibitors. 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
ANA-AS-71300 Sensolyte® Cell Viability and Proliferation Assay Kit 1 kit Anaspec The SensoLyte® Cell Viability and Proliferation Assay Kit provides researchers with a convenient one-solution and one-step assay to count living cells in a culture and continuously monitor cell proliferation over time by measuring cytoplasmic LDH activity. In this kit, resazurin is used as a sensitive fluorogenic indicator. Resazurin is converted to the strongly fluorescent resorufin (Ex/Em=560nm/590 nm) by cytoplasmic LDH. The kit can detect as few as 48 living cells with a linear range up to 5X104 cells (R2=0.99). This kit can also be used for high throughput screening of cell proliferation or measuring cytotoxicity effect of a variety of compounds. 384-well or 1536-well format can be used with minor modifications. Kit Size: 2000 assays This assay is also available in a larger size (10,000 assays) 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
ANA-AS-71302 Sensolyte® Cell Cytotoxicity Assay Kit 1 kit Anaspec The SensoLyte® Cell Cytotoxicity Assay Kit uses resazurin as a sensitive fluorogenic indicator (Ex/Em=560 nm/590 nm upon conversion) to measure LDH activity. The assay can be performed in a mixed population of damaged and viable cells, but it only measures the LDH released from damaged cells. The cytoplasmic LDH in living cells produces little signals under assay condition. There is no need for extra steps to separate living cells and supernatant. The fluorescent signal is proportional to the number of damaged cells (up to 2.5X104 cell, r2>0.95) with the detection limit reaching 100 dead cells. The kit is suitable for high throughput screening of cytotoxicity of a variety of compounds. 384-well or 1536-well format can be used with minor modifications. Kit Size: 500 assays 수량증가수량감소 카트담기 카트담기
견적문의 견적문의
전체선택
SensoLyte® AMC Caspase Profiling Kit *Fluorimetric*
Cat No.
ANA-AS-71120
규격
1 kit
제조사
Anaspec
제품정보
The SensoLyte® Caspase Profiling Kit contains a series of AMC-based peptide substrates as fluorogenic indicators for assaying caspase protease activities. The kit contains a well-designed plate in which a series of AMC-based caspase substrates are coated with both positive and negative controls. It provides the best solution for profiling caspases or caspase inhibitors. *384-well plate format is available on custom basis. Kit Size: 2 plates
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SensoLyte® Homogeneous AMC Caspase-3/7 Assay Kit
Cat No.
ANA-AS-71118
규격
1 kit
제조사
Anaspec
제품정보
The SensoLyte® Homogeneous AMC Capase-3/7 Assay Kit uses Ac-DEVD-AMC as the fluorogenic indicator for assaying caspase-3/7 activities. Upon caspase-3/7 cleavage, Ac-DEVD-AMC generates the AMC fluorophore which has bright blue fluorescence and can be detected at Ex/Em=354 nm/442 nm. A bi-function assay buffer in this kit is designed to lyze the cells and measure the enzyme activity at the same time. Thus, this kit can measure caspase-3/7 activity in cell culture directly in a 96-well or 384-well plate without a time-consuming cell extraction step. In case the cells are cultured in larger plates or flasks, a lysis buffer and protocol for cell lysate preparation are also conveniently included in the kit. The kit is suitable for high throughput screening of apoptosis inducers and inhibitors.
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Sensolyte® Cell Viability and Proliferation Assay Kit
Cat No.
ANA-AS-71300
규격
1 kit
제조사
Anaspec
제품정보
The SensoLyte® Cell Viability and Proliferation Assay Kit provides researchers with a convenient one-solution and one-step assay to count living cells in a culture and continuously monitor cell proliferation over time by measuring cytoplasmic LDH activity. In this kit, resazurin is used as a sensitive fluorogenic indicator. Resazurin is converted to the strongly fluorescent resorufin (Ex/Em=560nm/590 nm) by cytoplasmic LDH. The kit can detect as few as 48 living cells with a linear range up to 5X104 cells (R2=0.99). This kit can also be used for high throughput screening of cell proliferation or measuring cytotoxicity effect of a variety of compounds. 384-well or 1536-well format can be used with minor modifications. Kit Size: 2000 assays This assay is also available in a larger size (10,000 assays)
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Sensolyte® Cell Cytotoxicity Assay Kit
Cat No.
ANA-AS-71302
규격
1 kit
제조사
Anaspec
제품정보
The SensoLyte® Cell Cytotoxicity Assay Kit uses resazurin as a sensitive fluorogenic indicator (Ex/Em=560 nm/590 nm upon conversion) to measure LDH activity. The assay can be performed in a mixed population of damaged and viable cells, but it only measures the LDH released from damaged cells. The cytoplasmic LDH in living cells produces little signals under assay condition. There is no need for extra steps to separate living cells and supernatant. The fluorescent signal is proportional to the number of damaged cells (up to 2.5X104 cell, r2>0.95) with the detection limit reaching 100 dead cells. The kit is suitable for high throughput screening of cytotoxicity of a variety of compounds. 384-well or 1536-well format can be used with minor modifications. Kit Size: 500 assays
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최근 본 제품