제품특징

High Quality 

- 고순도의 펩타이드 제공 (Purity: ≥95% by HPLC) 

- ISO 9001 certified

Peptide Potential Anti-Diabetic Roles

Peptide Case Study

- Incretin Peptides (GIP & GLP-1)

 Incretins stimulate insulin release but inhibit glucagon release resulting in lower blood sugar. Glucagon is a peptide hormone secreted from the pancreas in response to low circulating blood glucose levels in order to restore normal glucose levels.

 The incretins, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are gastro-intestinal derived hormones that are released following meal ingestion in an attempt to regulate postprandial secretion of insulin (insulinotropic incretin effect)1. These incretins have several actions by peripheral and central mechanisms including regulating appetite and body weight. Furthermore, targeting the incretin system appears to provide a basis for not only the understanding of its relation to obesity among diabetic patients but also as a therapeutic strategy for obesity and diabetes with promising benefits in addition to weight loss.

Baggio LL, et al. Gastroenterology 132(6):2131-57 (2007).

Citations 

Amylins

Pilkington, EH. Et al. (2017). Effects of Protein Corona on IAPP Amyloid Aggregation, Fibril Remodelling, and Cytotoxicity. Sci Rep 7(1):2455. doi: 10.1038/s41598-017-02597-0.

Wang, M. et al. (2017). Differential effects of silver and iron oxide nanoparticles on IAPP amyloid aggregation. Biomater Sci. 5(3):485-493. doi: 10.1039/c6bm00764c. 

Exendins

Potthoff, MJ. et al. (2013). Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice. Am J Physiol Gastrointest Liver Physiol 304, G371. doi: 10.1152/ajpgi.00400.2012.

Ding, J. et al. (2009). Pax6 haploinsufficiency causes abnormal metabolic homeostasis by down-regulating GLP-1 in mice. Endocrin. doi:10.1210/en.2008-1006. 

Glucagon (1-37)

Sloan, JH., et al. (2012) A novel high-sensitivity electrochemiluminescence (ECL) sandwich immunoassay for the specific quantitative measurement of plasma glucagon. Clin Biochem 45(18):1640 doi: 10.1016/j.clinbiochem.2012.07.111.

GLP-1

Tashiro Y et al. (2014) A glucagon-like peptide-1 analog liraglutide suppresses macrophage foam cell formation and atherosclerosis; Peptides 54, 19-26.

주문정보

	Cat No.	품명	규격	제조사	제품정보	수량	견적문의
	AS-63714	[Cys(HiLyteᵀᴹ Fluor 647 C2 maleimide)] - Exendin - 4	50 ug	Anaspec	This peptide is HiLyte Fluor 647 labeled Extendin-4 (Ex/Em=650 nm/675 nm). A cysteine residue has been added to the peptide N-terminus, and the dye is conjugated to this cysteine via the cysteine thiol moiety. Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent.		카트담기 견적문의
	AS-64488	[FAM - Trp31] - GLP - 1 (7 - 36), Fluorescent label at Trp31	0.5 mg	Anaspec	This GLP-1 (7-36) amide peptide is fluorescently labeled at Tryptophan residue 25 with Fluorescein. This is the same type of fluorescent labeling as in Extendin-4 Flex peptide (Cat# AS-63899). GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide (cat# AS-22460). Both GLP-1 (7-36) and GLP-1 (7-37) - Cat# AS-20761, also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36) - Cat# AS-65070 (some studies suggest it may have weak insulinotropic activity). As a result, the majority of GLP-1 (and GIP) is inactivated as an insulinotrope before reaching the systemic circulation.		카트담기 견적문의
	AS-61937	[NMeG24, NMeI26] Human Islet Amyloid Polypeptide (IAPP) (22 - 27)	1 mg	Anaspec	This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.		카트담기 견적문의
	AS-60804	Amylin (1 - 37), human	1 mg	Anaspec	This peptide is a major constituent of protein deposits identified in the Islets of Langerhans of patients with noninsulin-dependent diabetes mellitus.		카트담기 견적문의
	AS-60254-1	Amylin (1 - 37), human, amide	1 mg	Anaspec	This peptide is a major constituent of protein deposits identified in the Islets of Langerhans of patients with noninsulin-dependent diabetes mellitus.		카트담기 견적문의
	AS-60253-05	Amylin (1 - 37), rat, mouse	0.5 mg	Anaspec	Rat/mouse Amylin differs from the human version in 6 amino acids: H18R, F23L, A25P, I26V, S28P and S29P (first letter is the amino acid of the human sequence). Unlike the human IAPP (Amylin), rat Amylin does not form amyloid fibers.		카트담기 견적문의
	AS-60253-1	Amylin (1 - 37), rat, mouse	1 mg	Anaspec	Rat/mouse Amylin differs from the human version in 6 amino acids: H18R, F23L, A25P, I26V, S28P and S29P (first letter is the amino acid of the human sequence). Unlike the human IAPP (Amylin), rat Amylin does not form amyloid fibers.		카트담기 견적문의
	AS-60259-1	Amylin (20 - 29), human	1 mg	Anaspec	This core region of human amylin, corresponding to amino acid residues 20 to 29, forms amyloid-like fibrils that display polymorphic structures.		카트담기 견적문의
	AS-21749	Amylin (8 - 37), rat	1 mg	Anaspec	This is a truncated peptide of native rat amylin. In-vivo and in-vitro studies suggest that it acts as a specific amylin antagonist. In isolated soleus muscle, it blocks amylin-induced inhibition of glycogen synthesis but has no effect in the absence of amylin. Amylin (8-37) increases whole body and muscle insulin sensitivity and consistently reduces basal insulin levels in normal and hGH-induced insulin-resistant rats. It also elicits a significant alteration of in-vivo lipid metabolism.		카트담기 견적문의
	AS-63774	BDC2.5 Mimotope	1 mg	Anaspec	The TCR transgenic model (BDC2.5) mimitope was used in type 1 diabetes (T1D) study. T1D is an autoimmune disease in which T cells mediate damage to pancreatic islet β cells. T1D is caused by autoreactive T cell destruction of insulin-producing cells. BDC2.5 mimotope was utilized to support the study on antigen presentation of antigenic peptides to islet autoantigen-specific T cells.		카트담기 견적문의
	AS-64451-05	Biotin - Amylin (1 - 37), amide, human	0.5 mg	Anaspec	This amidated amylin (1-37) peptide has a biotin conjugated on the N-terminus. Amylin (1-37) or IAPP (Islet Amyloid Polypeptide Precursor) is a major constituent of protein deposits identified in the Islets of Langerhans of patients with noninsulin-dependent diabetes mellitus.		카트담기 견적문의
	AS-60279-05	Biotin - Exendin 4	0.5 mg	Anaspec	This peptide, Exendin-4, has a biotin on the N-terminus. Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent.		카트담기 견적문의
	AS-60279-1	Biotin - Exendin 4	1 mg	Anaspec	This peptide, Exendin-4, has a biotin on the N-terminus. Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent.		카트담기 견적문의
	AS-60274-05	Biotin - Glucagon (1 - 29), bovine, human, porcine	0.5 mg	Anaspec	This is N-terminal biotin labeled Glucagon (1-29). Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia.		카트담기 견적문의
	AS-60274-1	Biotin - Glucagon (1 - 29), bovine, human, porcine	1 mg	Anaspec	This is N-terminal biotin labeled Glucagon (1-29). Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia.		카트담기 견적문의
	AS-23586	Biotin - Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human	0.5 mg	Anaspec	This GLP-1 (7-36) amide, is labeled with biotin at the peptide N-terminus. GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide (Cat# AS-22460). Both GLP-1 (7-36) and GLP-1 (7-37)-Cat# AS-20761, also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36)-Cat# AS-65070 (some studies suggest it may have weak insulinotropic activity). As a result, the majority of GLP-1 (and GIP) is inactivated as an insulinotrope before reaching the systemic circulation.		카트담기 견적문의
	AS-61127	C - peptide (57 - 87), human	0.5 mg	Anaspec	C-peptide is cleaved from proinsulin, stored in secretory granules, and eventually released into the bloodstream in amounts equimolar with those of insulin. The measurement of the C-peptide is an important test for the β-cell function. In the red blood cells of type 2 diabetic patients, Na+,K+ ATPase activity is strongly related to blood C-peptide levels. C-peptide signal transduction in human renal tubular cells involves the activation of phospholipase C and PKC-δ and PKC-varepsilon, as well as RhoA, followed by phosphorylation of ERK1/2 and JNK and a parallel activation of Akt. C-peptide shows specific binding to a G-protein-coupled membrane binding site, resulting in Ca2+ influx, activation of mitogen-activated protein kinase signalling pathways and stimulation of Na+, K+ ATPase and endothelial nitric oxide synthase.		카트담기 견적문의
	AS-61128	C - peptide, dog	0.5 mg	Anaspec	Insulin secretory rate can be estimated from peripheral C-peptide concentrations in dogs. Plasma C-peptide concentrations during glucagon stimulation testing is variable in diabetic dogs and may represent dogs with type-1 and type-2 diabetes or more likely, differences in severity of β-cell loss in dogs with type-1 diabetes.		카트담기 견적문의
	AS-63697	C - Peptide - 1, rat	0.5 mg	Anaspec	This is amino acid sequence of rat C-peptide-1. C-peptide binds specifically to cell surfaces, probably to a G protein-coupled surface receptor, with subsequent activation of Ca2+-dependent intracellular signaling pathways. It also stimulates Na+-K+-ATPase and endothelial nitric oxide synthase activities. Rat C-peptide was found to diminish glucose-stimulated insulin release in rats both in vivo and in vitro		카트담기 견적문의
	AS-63698	C - Peptide - 2, rat	0.5 mg	Anaspec	This rat C-peptide-2 differs from the active human C-peptide by several amino acids, however conserved Glu at positions 3, 11, and 27 is essential for peptide activity. In rat medullary thick ascending limb, C-peptide stimulates Na+,K+-ATPase activity within a physiological concentration range. This effect is due to an increase in Na+,K+-ATPase turnover rate that is most likely mediated by protein kinase C-f phosphorylation of the Na+,K+-ATPase f-subunit		카트담기 견적문의
	AS-63898	Exendin (5 - 39)	1 mg	Anaspec	This truncated Exendin-4 peptide, Exendin (5-39) amide, is a potent Glucagon-Like Peptide 1 (GLP-1) receptor antagonist. Unlike the full length Exendin-4 (a GLP-1 agonist), Exendin (5-39) antagonizes GLP-1–stimulated insulin release after food intake.		카트담기 견적문의
	AS-24467	Exendin (9 - 39)	0.5 mg	Anaspec	This truncated Exendin-4 peptide, Exendin (9-39) amide, is a potent Glucagon-Like Peptide 1 (GLP-1) receptor antagonist. Unlike the full length Exendin-4 (a GLP-1 agonist), Exendin (9-39) antagonizes GLP-1–stimulated insulin release after food intake. It is a competitive inhibitor of Exendin-3 and Exendin-4.		카트담기 견적문의
	AS-24468	Exendin (9 - 39)	1 mg	Anaspec	This truncated Exendin-4 peptide, Exendin (9-39) amide, is a potent Glucagon-Like Peptide 1 (GLP-1) receptor antagonist. Unlike the full length Exendin-4 (a GLP-1 agonist), Exendin (9-39) antagonizes GLP-1–stimulated insulin release after food intake. It is a competitive inhibitor of Exendin-3 and Exendin-4.		카트담기 견적문의
	AS-24463	Exendin 4	0.5 mg	Anaspec	Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent.		카트담기 견적문의
	AS-24464	Exendin 4	1 mg	Anaspec	Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent.		카트담기 견적문의
	AS-60280-05	Exendin 4, FAM - labeled	0.5 mg	Anaspec	This full length Exendin 4 amide peptide is labeled with a fluorescent dye (FAM), Abs/Em = 494/519 nm, on its N-terminus. Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent.		카트담기 견적문의
	AS-63899	Fluorescein - Trp25 - Exendin - 4 (FLEX)	0.5 mg	Anaspec	This peptide is Exendin-4 labeled with fluorescein at the Tryptophan residue. FLEX is equipotent to GLP-1(7-36)-amide and exendin-4 as an inhibitor of [125I] GLP-1 binding to the human GLP-1 receptor stably expressed in CHO cells, and maintains full biological potency and efficacy as measured by the stimulation of cAMP accumulation in these cells. FLEX binding to CHO/hGLP-1R membranes results in an increase in fluorescence anisotropy. The binding is specific and saturable (Kd = 2.0 +/- 0.4 nM), and GLP-1(7-36)-amide and Exendin-4 are equipotent inhibitors of FLEX binding to the human GLP-1 receptor. Thus, FLEX is a potent, biologically active ligand that is useful for the study of the binding and functional characteristics of the human GLP-1 receptor.		카트담기 견적문의
	AS-61226-05	GIP (1 - 42), human	0.5 mg	Anaspec	GIP (Glucose-dependent Insulinotropic Polypeptide or also known as Gastric Inhibitory Polypeptide) is a 42-amino acid peptide released by the K cells of the duodenum and jejunum in response to food intake. GIP, together with GLP (Gastric-like Peptide) are members of the hormone peptide family of Incretins which stimulate insulin secretion from pancreatic islet β-cells, and also appears to promote beta cell proliferation and beta cell survival. Recent studies suggest that GIP plays a role in lipid homeostasis and possibly in the pathogenesis of obesity.		카트담기 견적문의
	AS-61226-1	GIP (1 - 42), human	1 mg	Anaspec	GIP (Glucose-dependent Insulinotropic Polypeptide or also known as Gastric Inhibitory Polypeptide) is a 42-amino acid peptide released by the K cells of the duodenum and jejunum in response to food intake. GIP, together with GLP (Gastric-like Peptide) are members of the hormone peptide family of Incretins which stimulate insulin secretion from pancreatic islet β-cells, and also appears to promote beta cell proliferation and beta cell survival. Recent studies suggest that GIP plays a role in lipid homeostasis and possibly in the pathogenesis of obesity.		카트담기 견적문의
	AS-61227	GIP (3 - 42), human	1 mg	Anaspec	This peptide is from amino acid 3-42 of the full length 42-amino acid long GIP (Glucose-dependent Insulinotropic Polypeptide or also known as Gastric Inhibitory Polypeptide). The in-vivo degradation of the first two N-terminal amino acids (Tyr-Ala) by the enzyme dipeptidyl peptidase IV (DPP IV) results in making GIP (3-42) a potent antagonist as opposed to the agonist full length GIP on the GIP receptor.		카트담기 견적문의
	AS-65568-1	GIP, rat	1 mg	Anaspec			카트담기 견적문의
	AS-65568-05	GIP, rat	0.5 mg	Anaspec			카트담기 견적문의
	AS-65070	GLP - 1(9 - 36), amide, human	1 mg	Anaspec	GLP-1 (9-36) is the result of the rapid degradation of GLP-1 (7-36)amide, by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. GLP-1 (9-36) accounts for the majority of GLP-1 that reaches the system circulation. Whereas GLP-1 (7-36) amide stimulates glucose-dependent insulin secretion and inhibits glucagon secretion, GLP-1(9-36)amide administration had no effect on glucose clearance or insulin secretion in humans. GLP-1(9-36)amide however was shown to exert cardioprotective actions in rodent hearts.		카트담기 견적문의
	AS-62068	GLP - 2 (1 - 34), Glucagon - Like Peptide - 2 (1 - 34), human	1 mg	Anaspec	Glucagon-like peptide-2 (GLP-2) promotes nutrient absorption via expansion of the mucosal epithelium by stimulation of crypt cell proliferation and inhibition of apoptosis in the small intestine. It also reduces epithelial permeability, and decreases meal-stimulated gastric acid secretion and gastrointestinal motility. GLP-2 promotes the expansion of the intestinal epithelium through stimulation of the GLP-2 receptor, a member of the glucagon-secretin G protein-coupled receptor superfamily.		카트담기 견적문의
	AS-22456	Glucagon (1 - 29), bovine, human, porcine	0.5 mg	Anaspec	Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia.		카트담기 견적문의
	AS-22457	Glucagon (1 - 29), bovine, human, porcine	1 mg	Anaspec	Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia.		카트담기 견적문의
	AS-60273-1	Glucagon (1 - 29), bovine, human, porcine, FAM - labeled	1 mg	Anaspec	This is a fluorescent (FAM)-labeled Glucagon peptide, Abs/Em=494/521 nm. Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia.		카트담기 견적문의
	AS-22455	Glucagon (1 - 37), Oxyntomodulin, porcine	1 mg	Anaspec	Following nutrient ingestion, both GLP-1, and Oxyntomodulin (OXM) are processed from proglucagon and secreted from the gut endocine L-cells. Oxyntomodulin (OXM) a 37-amino acid peptide hormone causes weight loss in humans and rodents. It activates both the glucagon-like peptide-1 receptor (GLP1R) and the glucagon receptor (GCGR). It contains the same sequence as Glucagon (1-29), but with an additional KRNKNNIA C-terminal sequence.		카트담기 견적문의
	AS-22462	Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human	0.5 mg	Anaspec	GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide (Cat# AS-22460). Both GLP-1 (7-36) and GLP-1 (7-37)-Cat# AS-20761, also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36)-Cat# AS-65070 (some studies suggest it may have weak insulinotropic activity). As a result, the majority of GLP-1 (and GIP) is inactivated as an insulinotrope before reaching the systemic circulation.		카트담기 견적문의
	AS-22463	Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human	1 mg	Anaspec	GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide (Cat# AS-22460). Both GLP-1 (7-36) and GLP-1 (7-37)-Cat# AS-20761, also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36)-Cat# AS-65070 (some studies suggest it may have weak insulinotropic activity). As a result, the majority of GLP-1 (and GIP) is inactivated as an insulinotrope before reaching the systemic circulation.		카트담기 견적문의
	AS-23642	Glucagon - Like Peptide 1, GLP - 1 (7 - 36) - Lys(Biotin), amide, human	0.5 mg	Anaspec			카트담기 견적문의
	AS-23643	Glucagon - Like Peptide 1, GLP - 1 (7 - 36) - Lys(Biotin), amide, human	1 mg	Anaspec	This GLP-1 (7-36) amide contains an additional Lysine (K) residue at its N-terminus, with Biotin coupled to the Lysine side chain. GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide (Cat# AS-22460). Both GLP-1 (7-36) and GLP-1 (7-37) - Cat# AS-20761, also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36) - Cat# AS-65070 (some studies suggest it may have weak insulinotropic activity). As a result, the majority of GLP-1 (and GIP) is inactivated as an insulinotrope before reaching the systemic circulation.		카트담기 견적문의
	AS-20761	Glucagon - Like Peptide 1, GLP - 1 (7 - 37)	0.5 mg	Anaspec	GLP-1 (7-37) is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of proglucagon. Both GLP-1 (7-36) and GLP-1 (7-37) play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. Although GLP-1 (7-37) is bioactive, it is available in lesser amounts than GLP-1 (7-36) and is not amidated.		카트담기 견적문의
	AS-20762	Glucagon - Like Peptide 1, GLP - 1 (7 - 37)	1 mg	Anaspec	GLP-1 (7-37) is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of proglucagon. Both GLP-1 (7-36) and GLP-1 (7-37) play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. Although GLP-1 (7-37) is bioactive, it is available in lesser amounts than GLP-1 (7-36) and is not amidated.		카트담기 견적문의
	AS-22460	Glucagon - Like Peptide 1, GLP - 1 amide, human	0.5 mg	Anaspec	In response to Glucose ingestion, proglucagon in the intestinal L cells is cleaved into GLP-1 (1-36). Prior to secretion into the circulation, GLP-1 (1-36) is further processed into amidated GLP-1 (7-36)-cat# AS-22462-and small amounts of glycine-extended GLP-1 (7-37)-cat# AS-20761. Both GLP-1 (7-36) and GLP-1 (7-37), causes glucose dependent release of insulin by pancreatic beta-cells. They also play a role in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 peptides such as GLP-1 (1-36) have been used to investigate restoration of pancreatic beta cell function. GLP-1 is also produced in the central nervous system.		카트담기 견적문의
	AS-23606	Glucagon - Like Peptide 1, GLP - 1 amide, human, FAM - labeled	0.5 mg	Anaspec	This is fluorescent GLP-1 labeled at the peptide C-terminus with FAM, Abs/Em=494/521 nm. In response to Glucose ingestion, proglucagon in the intestinal L cells is cleaved into GLP-1 (1-36). Prior to secretion into the circulation, GLP-1 (1-36) is further processed into amidated GLP-1 (7-36)-cat# AS-22462-and small amounts of glycine-extended GLP-1 (7-37)-cat# AS-20761. Both GLP-1 (7-36) and GLP-1 (7-37), causes glucose dependent release of insulin by pancreatic beta-cells. They also play a role in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 peptides such as GLP-1 (1-36) have been used to investigate restoration of pancreatic beta cell function. GLP-1 is also produced in the central nervous system.		카트담기 견적문의
	AS-23607	Glucagon - Like Peptide 1, GLP - 1 amide, human, FAM - labeled	1 mg	Anaspec	This is fluorescent GLP-1 labeled at the peptide C-terminus with FAM, Abs/Em=494/521 nm. In response to Glucose ingestion, proglucagon in the intestinal L cells is cleaved into GLP-1 (1-36). Prior to secretion into the circulation, GLP-1 (1-36) is further processed into amidated GLP-1 (7-36)-cat# AS-22462-and small amounts of glycine-extended GLP-1 (7-37)-cat# AS-20761. Both GLP-1 (7-36) and GLP-1 (7-37), causes glucose dependent release of insulin by pancreatic beta-cells. They also play a role in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 peptides such as GLP-1 (1-36) have been used to investigate restoration of pancreatic beta cell function. GLP-1 is also produced in the central nervous system.		카트담기 견적문의
	AS-64431	IGRP Catalytic Subunit - related Protein (206 - 214)	1 mg	Anaspec	This peptide is the ?-cell peptide corresponding to residues 206–214 of murine islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP). This peptide is T cells specific for proinsulin and islet-specific glucose-6-phosphatase catalytic subunit related protein (IGRP) induce diabetes in non-obese diabetic (NOD) mice.		카트담기 견적문의
	AS-63773	Insulin β Chain Peptide (15 - 23)	1 mg	Anaspec	This is amino acids 15 to 23 fragment of the insulin β chain recognized by islet-associated T cells. This peptide is also known as INS. It was used in diabetes studies to assay the IFN-β and IL-17 production by diabetogenic CD4 or CD8 T cells. This peptide stains the INS-reactive CTL clone, but doesn’t stain the splenic CD8+ T cells from NOD or 8.3-TCR-transgenic NOD mice.		카트담기 견적문의
	AS-61532	Insulin B (9 - 23)	1 mg	Anaspec	This insulin B-chain peptide binds to a class II histocompatibility complex (MHC) allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic ß cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis.		카트담기 견적문의
	AS-22866	Pancreatic Polypeptide, human	0.5 mg	Anaspec	Pancreatic Polypeptide (PP) is a 36-amino acid anorexigenic peptide hormone secreted by the PP cells of pancreas. It is rapidly released postprandially and continues to remain elevated for approximately 4-6 hours after a meal. PP modulates food intake, and is absent in children with Prader-Willi syndrome. Secretion of PP can be accomplisehd through electrical stimulation of the vagus nerve. Cholecystokinin (CCK) and Gastrin appear to be involved in its secretion, while Ghrelin and Obestatin are reported to inhibit its release. PP is related to Peptide YY and Neuropeptide Y (NPY).		카트담기 견적문의
	AS-22867	Pancreatic Polypeptide, human	1 mg	Anaspec	Pancreatic Polypeptide (PP) is a 36-amino acid anorexigenic peptide hormone secreted by the PP cells of pancreas. It is rapidly released postprandially and continues to remain elevated for approximately 4-6 hours after a meal. PP modulates food intake, and is absent in children with Prader-Willi syndrome. Secretion of PP can be accomplisehd through electrical stimulation of the vagus nerve. Cholecystokinin (CCK) and Gastrin appear to be involved in its secretion, while Ghrelin and Obestatin are reported to inhibit its release. PP is related to Peptide YY and Neuropeptide Y (NPY).		카트담기 견적문의
	AS-24405	Peptide YY (3 - 36), human	0.5 mg	Anaspec	This peptide, a PYY (3-36), a Y2R agonist, is released from the gastrointestinal tract postprandially in proportion to the calorie content of a meal and can inhibit food intake.		카트담기 견적문의
	AS-24406	Peptide YY (3 - 36), human	1 mg	Anaspec	This peptide, a PYY (3-36), a Y2R agonist, is released from the gastrointestinal tract postprandially in proportion to the calorie content of a meal and can inhibit food intake.		카트담기 견적문의
	AS-24401	Peptide YY, human	0.5 mg	Anaspec	PYY is a 36-amino acid regulatory gut hormone present in endocrine cells in the intestine. This peptide acts both as an endocrine and a paracrine agent.		카트담기 견적문의
	AS-24402	Peptide YY, human	1 mg	Anaspec	PYY is a 36-amino acid regulatory gut hormone present in endocrine cells in the intestine. This peptide acts both as an endocrine and a paracrine agent.		카트담기 견적문의
	AS-64576-1	Pramlintide, Acetate [Pro25, 28, 29] - Amylin(1 - 37), human, Amide	1 mg	Anaspec	Pramlintide is the first in the new class of amylinomimetic compounds and is a synthetic analogue of the human hormone Amylin, a 37 amino acid peptide. Pramlintide’s peptide sequence differs from Amylin by replacing proline at postitions 25, 28, and 29. Pramlintide has a disulfide bridge between C2 and C7. For Research Use Only.		카트담기 견적문의
	AS-61129	Proinsulin C - Peptide (31 - 63), porcine	0.5 mg	Anaspec			카트담기 견적문의
	AS-61130	Proinsulin C - peptide (55 - 89), human	0.5 mg	Anaspec			카트담기 견적문의
	AS-24277	Somatostatin 14, human, rat, mouse, pig, chicken, frog	1 mg	Anaspec	Somatostatin [SST, GHIH (growth hormone-inhibiting hormone) or SRIF (somatotropin release-inhibiting factor)] is a cyclic peptide existing in two isoforms and is produced in the pancreas islet, GI tract and the central nervous system. Tetradecapeptide Somatostatin-14 (SRIF-14, the originally identified somatostatin) and the 28-amino acid Somatostatin-28 (SRIF-28) have similar biological activities but differ in their potency. Somatostatins inhibit the release of growth hormone in contrast to Growth Hormone Factor (GRF), which stimulates the release of growth hormone. Somatostatins also inhibit the release of prolactin and thyrotropin, peptide hormones from the pituitary gland and glucagon and insulin from the pancreas. It also controls the secretion of gut hormones and functions as a neurotransmitter.		카트담기 견적문의
	AS-24278	Somatostatin 14, human, rat, mouse, pig, chicken, frog	5 mg	Anaspec	Somatostatin [SST, GHIH (growth hormone-inhibiting hormone) or SRIF (somatotropin release-inhibiting factor)] is a cyclic peptide existing in two isoforms and is produced in the pancreas islet, GI tract and the central nervous system. Tetradecapeptide Somatostatin-14 (SRIF-14, the originally identified somatostatin) and the 28-amino acid Somatostatin-28 (SRIF-28) have similar biological activities but differ in their potency. Somatostatins inhibit the release of growth hormone in contrast to Growth Hormone Factor (GRF), which stimulates the release of growth hormone. Somatostatins also inhibit the release of prolactin and thyrotropin, peptide hormones from the pituitary gland and glucagon and insulin from the pancreas. It also controls the secretion of gut hormones and functions as a neurotransmitter.		카트담기 견적문의
	AS-22901	Somatostatin 28, human, sheep, cow, rat, mouse, pig	0.5 mg	Anaspec	Somatostatin [SST, GHIH (growth hormone-inhibiting hormone) or SRIF (somatotropin release-inhibiting factor)] is a cyclic peptide existing in two isoforms and is produced in the pancreas islet, GI tract and the central nervous system. Tetradecapeptide Somatostatin-14 (SRIF-14, the originally identified somatostatin) and the 28-amino acid Somatostatin-28 (SRIF-28) have similar biological activities but differ in their potency. Somatostatins inhibit the release of growth hormone in contrast to Growth Hormone Factor (GRF), which stimulates the release of growth hormone. Somatostatins also inhibit the release of prolactin and thyrotropin, peptide hormones from the pituitary gland and glucagon and insulin from the pancreas. It also controls the secretion of gut hormones and functions as a neurotransmitter.		카트담기 견적문의
	AS-22902	Somatostatin 28, human, sheep, cow, rat, mouse, pig	1 mg	Anaspec	Somatostatin [SST, GHIH (growth hormone-inhibiting hormone) or SRIF (somatotropin release-inhibiting factor)] is a cyclic peptide existing in two isoforms and is produced in the pancreas islet, GI tract and the central nervous system. Tetradecapeptide Somatostatin-14 (SRIF-14, the originally identified somatostatin) and the 28-amino acid Somatostatin-28 (SRIF-28) have similar biological activities but differ in their potency. Somatostatins inhibit the release of growth hormone in contrast to Growth Hormone Factor (GRF), which stimulates the release of growth hormone. Somatostatins also inhibit the release of prolactin and thyrotropin, peptide hormones from the pituitary gland and glucagon and insulin from the pancreas. It also controls the secretion of gut hormones and functions as a neurotransmitter.		카트담기 견적문의
	AS-65569	Spexin (36 - 49), amidated, human/mouse/rat	1 mg	Anaspec	Spexin is a novel peptide hormone that is derived from prohormone proNPQ and is conserved amongst mammalian species. Spexin (36-49) is post-translationally amidated with a C-terminal amidation processing signal motif (GRR) following Q49 residue of the pro-hormone. Spexin reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents. Recently it was suggested that this peptide may play a role in lipid and glucose metabolism in patients with type-2 diabetes mellitus.		카트담기 견적문의
	AS-65570	Spexin - 2 (53 - 70), amidated, human/mouse/rat	1 mg	Anaspec	This is amidated Spexin-2 (53-70) peptide showing similar biological function as that of its non- amidated version (Cat # 65586) as a central modulator of cardiovascular and renal function. Spexin-2 is a novel peptide hormone that is derived from prohormone proNPQ and is conserved amongst mammalian species.		카트담기 견적문의
	AS-65586	Spexin - 2 (53 - 70), human/mouse/rat	1 mg	Anaspec	This is Spexin-2 (53-70), non-amidated version of the novel peptide hormone that is derived from prohormone proNPQ and is conserved amongst mammalian species. It is a central modulator of cardiovascular and renal function. Spexin-2, when administered to rats, decreases heart rate and increases urine flow rate		카트담기 견적문의
	AS-62072	Trp Cage	1 mg	Anaspec	This peptide is a C-terminal fragment of exendin-4. This 20-residue construct is over 95% folded in water at physiological pH, and exhibits a tightly folded tertiary structure in solution. Trp Cage is a highly stable mini-protein fold. It consists of a short helix, a 3,10 helix and a C-terminal poly-proline that packs against a Trp in the alpha helix. It is known to fold within 4 nanoseconds. This stable fast-folding Trp Cage sequence displays special stabilizing features specific to this miniprotein.		카트담기 견적문의

	전체선택
	[Cys(HiLyteᵀᴹ Fluor 647 C2 maleimide)] - Exendin - 4 Cat No. AS-63714 규격 50 ug 제조사 Anaspec 제품정보 This peptide is HiLyte Fluor 647 labeled Extendin-4 (Ex/Em=650 nm/675 nm). A cysteine residue has been added to the peptide N-terminus, and the dye is conjugated to this cysteine via the cysteine thiol moiety. Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent. 수량 카트담기 견적문의
	[FAM - Trp31] - GLP - 1 (7 - 36), Fluorescent label at Trp31 Cat No. AS-64488 규격 0.5 mg 제조사 Anaspec 제품정보 This GLP-1 (7-36) amide peptide is fluorescently labeled at Tryptophan residue 25 with Fluorescein. This is the same type of fluorescent labeling as in Extendin-4 Flex peptide (Cat# AS-63899). GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide (cat# AS-22460). Both GLP-1 (7-36) and GLP-1 (7-37) - Cat# AS-20761, also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36) - Cat# AS-65070 (some studies suggest it may have weak insulinotropic activity). As a result, the majority of GLP-1 (and GIP) is inactivated as an insulinotrope before reaching the systemic circulation. 수량 카트담기 견적문의
	[NMeG24, NMeI26] Human Islet Amyloid Polypeptide (IAPP) (22 - 27) Cat No. AS-61937 규격 1 mg 제조사 Anaspec 제품정보 This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis. 수량 카트담기 견적문의
	Amylin (1 - 37), human Cat No. AS-60804 규격 1 mg 제조사 Anaspec 제품정보 This peptide is a major constituent of protein deposits identified in the Islets of Langerhans of patients with noninsulin-dependent diabetes mellitus. 수량 카트담기 견적문의
	Amylin (1 - 37), human, amide Cat No. AS-60254-1 규격 1 mg 제조사 Anaspec 제품정보 This peptide is a major constituent of protein deposits identified in the Islets of Langerhans of patients with noninsulin-dependent diabetes mellitus. 수량 카트담기 견적문의
	Amylin (1 - 37), rat, mouse Cat No. AS-60253-05 규격 0.5 mg 제조사 Anaspec 제품정보 Rat/mouse Amylin differs from the human version in 6 amino acids: H18R, F23L, A25P, I26V, S28P and S29P (first letter is the amino acid of the human sequence). Unlike the human IAPP (Amylin), rat Amylin does not form amyloid fibers. 수량 카트담기 견적문의
	Amylin (1 - 37), rat, mouse Cat No. AS-60253-1 규격 1 mg 제조사 Anaspec 제품정보 Rat/mouse Amylin differs from the human version in 6 amino acids: H18R, F23L, A25P, I26V, S28P and S29P (first letter is the amino acid of the human sequence). Unlike the human IAPP (Amylin), rat Amylin does not form amyloid fibers. 수량 카트담기 견적문의
	Amylin (20 - 29), human Cat No. AS-60259-1 규격 1 mg 제조사 Anaspec 제품정보 This core region of human amylin, corresponding to amino acid residues 20 to 29, forms amyloid-like fibrils that display polymorphic structures. 수량 카트담기 견적문의
	Amylin (8 - 37), rat Cat No. AS-21749 규격 1 mg 제조사 Anaspec 제품정보 This is a truncated peptide of native rat amylin. In-vivo and in-vitro studies suggest that it acts as a specific amylin antagonist. In isolated soleus muscle, it blocks amylin-induced inhibition of glycogen synthesis but has no effect in the absence of amylin. Amylin (8-37) increases whole body and muscle insulin sensitivity and consistently reduces basal insulin levels in normal and hGH-induced insulin-resistant rats. It also elicits a significant alteration of in-vivo lipid metabolism. 수량 카트담기 견적문의
	BDC2.5 Mimotope Cat No. AS-63774 규격 1 mg 제조사 Anaspec 제품정보 The TCR transgenic model (BDC2.5) mimitope was used in type 1 diabetes (T1D) study. T1D is an autoimmune disease in which T cells mediate damage to pancreatic islet β cells. T1D is caused by autoreactive T cell destruction of insulin-producing cells. BDC2.5 mimotope was utilized to support the study on antigen presentation of antigenic peptides to islet autoantigen-specific T cells. 수량 카트담기 견적문의
	Biotin - Amylin (1 - 37), amide, human Cat No. AS-64451-05 규격 0.5 mg 제조사 Anaspec 제품정보 This amidated amylin (1-37) peptide has a biotin conjugated on the N-terminus. Amylin (1-37) or IAPP (Islet Amyloid Polypeptide Precursor) is a major constituent of protein deposits identified in the Islets of Langerhans of patients with noninsulin-dependent diabetes mellitus. 수량 카트담기 견적문의
	Biotin - Exendin 4 Cat No. AS-60279-05 규격 0.5 mg 제조사 Anaspec 제품정보 This peptide, Exendin-4, has a biotin on the N-terminus. Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent. 수량 카트담기 견적문의
	Biotin - Exendin 4 Cat No. AS-60279-1 규격 1 mg 제조사 Anaspec 제품정보 This peptide, Exendin-4, has a biotin on the N-terminus. Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent. 수량 카트담기 견적문의
	Biotin - Glucagon (1 - 29), bovine, human, porcine Cat No. AS-60274-05 규격 0.5 mg 제조사 Anaspec 제품정보 This is N-terminal biotin labeled Glucagon (1-29). Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia. 수량 카트담기 견적문의
	Biotin - Glucagon (1 - 29), bovine, human, porcine Cat No. AS-60274-1 규격 1 mg 제조사 Anaspec 제품정보 This is N-terminal biotin labeled Glucagon (1-29). Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia. 수량 카트담기 견적문의
	Biotin - Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human Cat No. AS-23586 규격 0.5 mg 제조사 Anaspec 제품정보 This GLP-1 (7-36) amide, is labeled with biotin at the peptide N-terminus. GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide (Cat# AS-22460). Both GLP-1 (7-36) and GLP-1 (7-37)-Cat# AS-20761, also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36)-Cat# AS-65070 (some studies suggest it may have weak insulinotropic activity). As a result, the majority of GLP-1 (and GIP) is inactivated as an insulinotrope before reaching the systemic circulation. 수량 카트담기 견적문의
	C - peptide (57 - 87), human Cat No. AS-61127 규격 0.5 mg 제조사 Anaspec 제품정보 C-peptide is cleaved from proinsulin, stored in secretory granules, and eventually released into the bloodstream in amounts equimolar with those of insulin. The measurement of the C-peptide is an important test for the β-cell function. In the red blood cells of type 2 diabetic patients, Na+,K+ ATPase activity is strongly related to blood C-peptide levels. C-peptide signal transduction in human renal tubular cells involves the activation of phospholipase C and PKC-δ and PKC-varepsilon, as well as RhoA, followed by phosphorylation of ERK1/2 and JNK and a parallel activation of Akt. C-peptide shows specific binding to a G-protein-coupled membrane binding site, resulting in Ca2+ influx, activation of mitogen-activated protein kinase signalling pathways and stimulation of Na+, K+ ATPase and endothelial nitric oxide synthase. 수량 카트담기 견적문의
	C - peptide, dog Cat No. AS-61128 규격 0.5 mg 제조사 Anaspec 제품정보 Insulin secretory rate can be estimated from peripheral C-peptide concentrations in dogs. Plasma C-peptide concentrations during glucagon stimulation testing is variable in diabetic dogs and may represent dogs with type-1 and type-2 diabetes or more likely, differences in severity of β-cell loss in dogs with type-1 diabetes. 수량 카트담기 견적문의
	C - Peptide - 1, rat Cat No. AS-63697 규격 0.5 mg 제조사 Anaspec 제품정보 This is amino acid sequence of rat C-peptide-1. C-peptide binds specifically to cell surfaces, probably to a G protein-coupled surface receptor, with subsequent activation of Ca2+-dependent intracellular signaling pathways. It also stimulates Na+-K+-ATPase and endothelial nitric oxide synthase activities. Rat C-peptide was found to diminish glucose-stimulated insulin release in rats both in vivo and in vitro 수량 카트담기 견적문의
	C - Peptide - 2, rat Cat No. AS-63698 규격 0.5 mg 제조사 Anaspec 제품정보 This rat C-peptide-2 differs from the active human C-peptide by several amino acids, however conserved Glu at positions 3, 11, and 27 is essential for peptide activity. In rat medullary thick ascending limb, C-peptide stimulates Na+,K+-ATPase activity within a physiological concentration range. This effect is due to an increase in Na+,K+-ATPase turnover rate that is most likely mediated by protein kinase C-f phosphorylation of the Na+,K+-ATPase f-subunit 수량 카트담기 견적문의
	Exendin (5 - 39) Cat No. AS-63898 규격 1 mg 제조사 Anaspec 제품정보 This truncated Exendin-4 peptide, Exendin (5-39) amide, is a potent Glucagon-Like Peptide 1 (GLP-1) receptor antagonist. Unlike the full length Exendin-4 (a GLP-1 agonist), Exendin (5-39) antagonizes GLP-1–stimulated insulin release after food intake. 수량 카트담기 견적문의
	Exendin (9 - 39) Cat No. AS-24467 규격 0.5 mg 제조사 Anaspec 제품정보 This truncated Exendin-4 peptide, Exendin (9-39) amide, is a potent Glucagon-Like Peptide 1 (GLP-1) receptor antagonist. Unlike the full length Exendin-4 (a GLP-1 agonist), Exendin (9-39) antagonizes GLP-1–stimulated insulin release after food intake. It is a competitive inhibitor of Exendin-3 and Exendin-4. 수량 카트담기 견적문의
	Exendin (9 - 39) Cat No. AS-24468 규격 1 mg 제조사 Anaspec 제품정보 This truncated Exendin-4 peptide, Exendin (9-39) amide, is a potent Glucagon-Like Peptide 1 (GLP-1) receptor antagonist. Unlike the full length Exendin-4 (a GLP-1 agonist), Exendin (9-39) antagonizes GLP-1–stimulated insulin release after food intake. It is a competitive inhibitor of Exendin-3 and Exendin-4. 수량 카트담기 견적문의
	Exendin 4 Cat No. AS-24463 규격 0.5 mg 제조사 Anaspec 제품정보 Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent. 수량 카트담기 견적문의
	Exendin 4 Cat No. AS-24464 규격 1 mg 제조사 Anaspec 제품정보 Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent. 수량 카트담기 견적문의
	Exendin 4, FAM - labeled Cat No. AS-60280-05 규격 0.5 mg 제조사 Anaspec 제품정보 This full length Exendin 4 amide peptide is labeled with a fluorescent dye (FAM), Abs/Em = 494/519 nm, on its N-terminus. Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent. 수량 카트담기 견적문의
	Fluorescein - Trp25 - Exendin - 4 (FLEX) Cat No. AS-63899 규격 0.5 mg 제조사 Anaspec 제품정보 This peptide is Exendin-4 labeled with fluorescein at the Tryptophan residue. FLEX is equipotent to GLP-1(7-36)-amide and exendin-4 as an inhibitor of [125I] GLP-1 binding to the human GLP-1 receptor stably expressed in CHO cells, and maintains full biological potency and efficacy as measured by the stimulation of cAMP accumulation in these cells. FLEX binding to CHO/hGLP-1R membranes results in an increase in fluorescence anisotropy. The binding is specific and saturable (Kd = 2.0 +/- 0.4 nM), and GLP-1(7-36)-amide and Exendin-4 are equipotent inhibitors of FLEX binding to the human GLP-1 receptor. Thus, FLEX is a potent, biologically active ligand that is useful for the study of the binding and functional characteristics of the human GLP-1 receptor. 수량 카트담기 견적문의
	GIP (1 - 42), human Cat No. AS-61226-05 규격 0.5 mg 제조사 Anaspec 제품정보 GIP (Glucose-dependent Insulinotropic Polypeptide or also known as Gastric Inhibitory Polypeptide) is a 42-amino acid peptide released by the K cells of the duodenum and jejunum in response to food intake. GIP, together with GLP (Gastric-like Peptide) are members of the hormone peptide family of Incretins which stimulate insulin secretion from pancreatic islet β-cells, and also appears to promote beta cell proliferation and beta cell survival. Recent studies suggest that GIP plays a role in lipid homeostasis and possibly in the pathogenesis of obesity. 수량 카트담기 견적문의
	GIP (1 - 42), human Cat No. AS-61226-1 규격 1 mg 제조사 Anaspec 제품정보 GIP (Glucose-dependent Insulinotropic Polypeptide or also known as Gastric Inhibitory Polypeptide) is a 42-amino acid peptide released by the K cells of the duodenum and jejunum in response to food intake. GIP, together with GLP (Gastric-like Peptide) are members of the hormone peptide family of Incretins which stimulate insulin secretion from pancreatic islet β-cells, and also appears to promote beta cell proliferation and beta cell survival. Recent studies suggest that GIP plays a role in lipid homeostasis and possibly in the pathogenesis of obesity. 수량 카트담기 견적문의
	GIP (3 - 42), human Cat No. AS-61227 규격 1 mg 제조사 Anaspec 제품정보 This peptide is from amino acid 3-42 of the full length 42-amino acid long GIP (Glucose-dependent Insulinotropic Polypeptide or also known as Gastric Inhibitory Polypeptide). The in-vivo degradation of the first two N-terminal amino acids (Tyr-Ala) by the enzyme dipeptidyl peptidase IV (DPP IV) results in making GIP (3-42) a potent antagonist as opposed to the agonist full length GIP on the GIP receptor. 수량 카트담기 견적문의
	GIP, rat Cat No. AS-65568-1 규격 1 mg 제조사 Anaspec 제품정보 수량 카트담기 견적문의
	GIP, rat Cat No. AS-65568-05 규격 0.5 mg 제조사 Anaspec 제품정보 수량 카트담기 견적문의
	GLP - 1(9 - 36), amide, human Cat No. AS-65070 규격 1 mg 제조사 Anaspec 제품정보 GLP-1 (9-36) is the result of the rapid degradation of GLP-1 (7-36)amide, by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. GLP-1 (9-36) accounts for the majority of GLP-1 that reaches the system circulation. Whereas GLP-1 (7-36) amide stimulates glucose-dependent insulin secretion and inhibits glucagon secretion, GLP-1(9-36)amide administration had no effect on glucose clearance or insulin secretion in humans. GLP-1(9-36)amide however was shown to exert cardioprotective actions in rodent hearts. 수량 카트담기 견적문의
	GLP - 2 (1 - 34), Glucagon - Like Peptide - 2 (1 - 34), human Cat No. AS-62068 규격 1 mg 제조사 Anaspec 제품정보 Glucagon-like peptide-2 (GLP-2) promotes nutrient absorption via expansion of the mucosal epithelium by stimulation of crypt cell proliferation and inhibition of apoptosis in the small intestine. It also reduces epithelial permeability, and decreases meal-stimulated gastric acid secretion and gastrointestinal motility. GLP-2 promotes the expansion of the intestinal epithelium through stimulation of the GLP-2 receptor, a member of the glucagon-secretin G protein-coupled receptor superfamily. 수량 카트담기 견적문의
	Glucagon (1 - 29), bovine, human, porcine Cat No. AS-22456 규격 0.5 mg 제조사 Anaspec 제품정보 Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia. 수량 카트담기 견적문의
	Glucagon (1 - 29), bovine, human, porcine Cat No. AS-22457 규격 1 mg 제조사 Anaspec 제품정보 Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia. 수량 카트담기 견적문의
	Glucagon (1 - 29), bovine, human, porcine, FAM - labeled Cat No. AS-60273-1 규격 1 mg 제조사 Anaspec 제품정보 This is a fluorescent (FAM)-labeled Glucagon peptide, Abs/Em=494/521 nm. Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia. 수량 카트담기 견적문의
	Glucagon (1 - 37), Oxyntomodulin, porcine Cat No. AS-22455 규격 1 mg 제조사 Anaspec 제품정보 Following nutrient ingestion, both GLP-1, and Oxyntomodulin (OXM) are processed from proglucagon and secreted from the gut endocine L-cells. Oxyntomodulin (OXM) a 37-amino acid peptide hormone causes weight loss in humans and rodents. It activates both the glucagon-like peptide-1 receptor (GLP1R) and the glucagon receptor (GCGR). It contains the same sequence as Glucagon (1-29), but with an additional KRNKNNIA C-terminal sequence. 수량 카트담기 견적문의
	Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human Cat No. AS-22462 규격 0.5 mg 제조사 Anaspec 제품정보 GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide (Cat# AS-22460). Both GLP-1 (7-36) and GLP-1 (7-37)-Cat# AS-20761, also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36)-Cat# AS-65070 (some studies suggest it may have weak insulinotropic activity). As a result, the majority of GLP-1 (and GIP) is inactivated as an insulinotrope before reaching the systemic circulation. 수량 카트담기 견적문의
	Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human Cat No. AS-22463 규격 1 mg 제조사 Anaspec 제품정보 GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide (Cat# AS-22460). Both GLP-1 (7-36) and GLP-1 (7-37)-Cat# AS-20761, also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36)-Cat# AS-65070 (some studies suggest it may have weak insulinotropic activity). As a result, the majority of GLP-1 (and GIP) is inactivated as an insulinotrope before reaching the systemic circulation. 수량 카트담기 견적문의
	Glucagon - Like Peptide 1, GLP - 1 (7 - 36) - Lys(Biotin), amide, human Cat No. AS-23642 규격 0.5 mg 제조사 Anaspec 제품정보 수량 카트담기 견적문의
	Glucagon - Like Peptide 1, GLP - 1 (7 - 36) - Lys(Biotin), amide, human Cat No. AS-23643 규격 1 mg 제조사 Anaspec 제품정보 This GLP-1 (7-36) amide contains an additional Lysine (K) residue at its N-terminus, with Biotin coupled to the Lysine side chain. GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide (Cat# AS-22460). Both GLP-1 (7-36) and GLP-1 (7-37) - Cat# AS-20761, also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36) - Cat# AS-65070 (some studies suggest it may have weak insulinotropic activity). As a result, the majority of GLP-1 (and GIP) is inactivated as an insulinotrope before reaching the systemic circulation. 수량 카트담기 견적문의
	Glucagon - Like Peptide 1, GLP - 1 (7 - 37) Cat No. AS-20761 규격 0.5 mg 제조사 Anaspec 제품정보 GLP-1 (7-37) is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of proglucagon. Both GLP-1 (7-36) and GLP-1 (7-37) play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. Although GLP-1 (7-37) is bioactive, it is available in lesser amounts than GLP-1 (7-36) and is not amidated. 수량 카트담기 견적문의
	Glucagon - Like Peptide 1, GLP - 1 (7 - 37) Cat No. AS-20762 규격 1 mg 제조사 Anaspec 제품정보 GLP-1 (7-37) is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of proglucagon. Both GLP-1 (7-36) and GLP-1 (7-37) play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. Although GLP-1 (7-37) is bioactive, it is available in lesser amounts than GLP-1 (7-36) and is not amidated. 수량 카트담기 견적문의
	Glucagon - Like Peptide 1, GLP - 1 amide, human Cat No. AS-22460 규격 0.5 mg 제조사 Anaspec 제품정보 In response to Glucose ingestion, proglucagon in the intestinal L cells is cleaved into GLP-1 (1-36). Prior to secretion into the circulation, GLP-1 (1-36) is further processed into amidated GLP-1 (7-36)-cat# AS-22462-and small amounts of glycine-extended GLP-1 (7-37)-cat# AS-20761. Both GLP-1 (7-36) and GLP-1 (7-37), causes glucose dependent release of insulin by pancreatic beta-cells. They also play a role in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 peptides such as GLP-1 (1-36) have been used to investigate restoration of pancreatic beta cell function. GLP-1 is also produced in the central nervous system. 수량 카트담기 견적문의
	Glucagon - Like Peptide 1, GLP - 1 amide, human, FAM - labeled Cat No. AS-23606 규격 0.5 mg 제조사 Anaspec 제품정보 This is fluorescent GLP-1 labeled at the peptide C-terminus with FAM, Abs/Em=494/521 nm. In response to Glucose ingestion, proglucagon in the intestinal L cells is cleaved into GLP-1 (1-36). Prior to secretion into the circulation, GLP-1 (1-36) is further processed into amidated GLP-1 (7-36)-cat# AS-22462-and small amounts of glycine-extended GLP-1 (7-37)-cat# AS-20761. Both GLP-1 (7-36) and GLP-1 (7-37), causes glucose dependent release of insulin by pancreatic beta-cells. They also play a role in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 peptides such as GLP-1 (1-36) have been used to investigate restoration of pancreatic beta cell function. GLP-1 is also produced in the central nervous system. 수량 카트담기 견적문의
	Glucagon - Like Peptide 1, GLP - 1 amide, human, FAM - labeled Cat No. AS-23607 규격 1 mg 제조사 Anaspec 제품정보 This is fluorescent GLP-1 labeled at the peptide C-terminus with FAM, Abs/Em=494/521 nm. In response to Glucose ingestion, proglucagon in the intestinal L cells is cleaved into GLP-1 (1-36). Prior to secretion into the circulation, GLP-1 (1-36) is further processed into amidated GLP-1 (7-36)-cat# AS-22462-and small amounts of glycine-extended GLP-1 (7-37)-cat# AS-20761. Both GLP-1 (7-36) and GLP-1 (7-37), causes glucose dependent release of insulin by pancreatic beta-cells. They also play a role in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. GLP-1 peptides such as GLP-1 (1-36) have been used to investigate restoration of pancreatic beta cell function. GLP-1 is also produced in the central nervous system. 수량 카트담기 견적문의
	IGRP Catalytic Subunit - related Protein (206 - 214) Cat No. AS-64431 규격 1 mg 제조사 Anaspec 제품정보 This peptide is the ?-cell peptide corresponding to residues 206–214 of murine islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP). This peptide is T cells specific for proinsulin and islet-specific glucose-6-phosphatase catalytic subunit related protein (IGRP) induce diabetes in non-obese diabetic (NOD) mice. 수량 카트담기 견적문의
	Insulin β Chain Peptide (15 - 23) Cat No. AS-63773 규격 1 mg 제조사 Anaspec 제품정보 This is amino acids 15 to 23 fragment of the insulin β chain recognized by islet-associated T cells. This peptide is also known as INS. It was used in diabetes studies to assay the IFN-β and IL-17 production by diabetogenic CD4 or CD8 T cells. This peptide stains the INS-reactive CTL clone, but doesn’t stain the splenic CD8+ T cells from NOD or 8.3-TCR-transgenic NOD mice. 수량 카트담기 견적문의
	Insulin B (9 - 23) Cat No. AS-61532 규격 1 mg 제조사 Anaspec 제품정보 This insulin B-chain peptide binds to a class II histocompatibility complex (MHC) allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic ß cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis. 수량 카트담기 견적문의
	Pancreatic Polypeptide, human Cat No. AS-22866 규격 0.5 mg 제조사 Anaspec 제품정보 Pancreatic Polypeptide (PP) is a 36-amino acid anorexigenic peptide hormone secreted by the PP cells of pancreas. It is rapidly released postprandially and continues to remain elevated for approximately 4-6 hours after a meal. PP modulates food intake, and is absent in children with Prader-Willi syndrome. Secretion of PP can be accomplisehd through electrical stimulation of the vagus nerve. Cholecystokinin (CCK) and Gastrin appear to be involved in its secretion, while Ghrelin and Obestatin are reported to inhibit its release. PP is related to Peptide YY and Neuropeptide Y (NPY). 수량 카트담기 견적문의
	Pancreatic Polypeptide, human Cat No. AS-22867 규격 1 mg 제조사 Anaspec 제품정보 Pancreatic Polypeptide (PP) is a 36-amino acid anorexigenic peptide hormone secreted by the PP cells of pancreas. It is rapidly released postprandially and continues to remain elevated for approximately 4-6 hours after a meal. PP modulates food intake, and is absent in children with Prader-Willi syndrome. Secretion of PP can be accomplisehd through electrical stimulation of the vagus nerve. Cholecystokinin (CCK) and Gastrin appear to be involved in its secretion, while Ghrelin and Obestatin are reported to inhibit its release. PP is related to Peptide YY and Neuropeptide Y (NPY). 수량 카트담기 견적문의
	Peptide YY (3 - 36), human Cat No. AS-24405 규격 0.5 mg 제조사 Anaspec 제품정보 This peptide, a PYY (3-36), a Y2R agonist, is released from the gastrointestinal tract postprandially in proportion to the calorie content of a meal and can inhibit food intake. 수량 카트담기 견적문의
	Peptide YY (3 - 36), human Cat No. AS-24406 규격 1 mg 제조사 Anaspec 제품정보 This peptide, a PYY (3-36), a Y2R agonist, is released from the gastrointestinal tract postprandially in proportion to the calorie content of a meal and can inhibit food intake. 수량 카트담기 견적문의
	Peptide YY, human Cat No. AS-24401 규격 0.5 mg 제조사 Anaspec 제품정보 PYY is a 36-amino acid regulatory gut hormone present in endocrine cells in the intestine. This peptide acts both as an endocrine and a paracrine agent. 수량 카트담기 견적문의
	Peptide YY, human Cat No. AS-24402 규격 1 mg 제조사 Anaspec 제품정보 PYY is a 36-amino acid regulatory gut hormone present in endocrine cells in the intestine. This peptide acts both as an endocrine and a paracrine agent. 수량 카트담기 견적문의
	Pramlintide, Acetate [Pro25, 28, 29] - Amylin(1 - 37), human, Amide Cat No. AS-64576-1 규격 1 mg 제조사 Anaspec 제품정보 Pramlintide is the first in the new class of amylinomimetic compounds and is a synthetic analogue of the human hormone Amylin, a 37 amino acid peptide. Pramlintide’s peptide sequence differs from Amylin by replacing proline at postitions 25, 28, and 29. Pramlintide has a disulfide bridge between C2 and C7. For Research Use Only. 수량 카트담기 견적문의
	Proinsulin C - Peptide (31 - 63), porcine Cat No. AS-61129 규격 0.5 mg 제조사 Anaspec 제품정보 수량 카트담기 견적문의
	Proinsulin C - peptide (55 - 89), human Cat No. AS-61130 규격 0.5 mg 제조사 Anaspec 제품정보 수량 카트담기 견적문의
	Somatostatin 14, human, rat, mouse, pig, chicken, frog Cat No. AS-24277 규격 1 mg 제조사 Anaspec 제품정보 Somatostatin [SST, GHIH (growth hormone-inhibiting hormone) or SRIF (somatotropin release-inhibiting factor)] is a cyclic peptide existing in two isoforms and is produced in the pancreas islet, GI tract and the central nervous system. Tetradecapeptide Somatostatin-14 (SRIF-14, the originally identified somatostatin) and the 28-amino acid Somatostatin-28 (SRIF-28) have similar biological activities but differ in their potency. Somatostatins inhibit the release of growth hormone in contrast to Growth Hormone Factor (GRF), which stimulates the release of growth hormone. Somatostatins also inhibit the release of prolactin and thyrotropin, peptide hormones from the pituitary gland and glucagon and insulin from the pancreas. It also controls the secretion of gut hormones and functions as a neurotransmitter. 수량 카트담기 견적문의
	Somatostatin 14, human, rat, mouse, pig, chicken, frog Cat No. AS-24278 규격 5 mg 제조사 Anaspec 제품정보 Somatostatin [SST, GHIH (growth hormone-inhibiting hormone) or SRIF (somatotropin release-inhibiting factor)] is a cyclic peptide existing in two isoforms and is produced in the pancreas islet, GI tract and the central nervous system. Tetradecapeptide Somatostatin-14 (SRIF-14, the originally identified somatostatin) and the 28-amino acid Somatostatin-28 (SRIF-28) have similar biological activities but differ in their potency. Somatostatins inhibit the release of growth hormone in contrast to Growth Hormone Factor (GRF), which stimulates the release of growth hormone. Somatostatins also inhibit the release of prolactin and thyrotropin, peptide hormones from the pituitary gland and glucagon and insulin from the pancreas. It also controls the secretion of gut hormones and functions as a neurotransmitter. 수량 카트담기 견적문의
	Somatostatin 28, human, sheep, cow, rat, mouse, pig Cat No. AS-22901 규격 0.5 mg 제조사 Anaspec 제품정보 Somatostatin [SST, GHIH (growth hormone-inhibiting hormone) or SRIF (somatotropin release-inhibiting factor)] is a cyclic peptide existing in two isoforms and is produced in the pancreas islet, GI tract and the central nervous system. Tetradecapeptide Somatostatin-14 (SRIF-14, the originally identified somatostatin) and the 28-amino acid Somatostatin-28 (SRIF-28) have similar biological activities but differ in their potency. Somatostatins inhibit the release of growth hormone in contrast to Growth Hormone Factor (GRF), which stimulates the release of growth hormone. Somatostatins also inhibit the release of prolactin and thyrotropin, peptide hormones from the pituitary gland and glucagon and insulin from the pancreas. It also controls the secretion of gut hormones and functions as a neurotransmitter. 수량 카트담기 견적문의
	Somatostatin 28, human, sheep, cow, rat, mouse, pig Cat No. AS-22902 규격 1 mg 제조사 Anaspec 제품정보 Somatostatin [SST, GHIH (growth hormone-inhibiting hormone) or SRIF (somatotropin release-inhibiting factor)] is a cyclic peptide existing in two isoforms and is produced in the pancreas islet, GI tract and the central nervous system. Tetradecapeptide Somatostatin-14 (SRIF-14, the originally identified somatostatin) and the 28-amino acid Somatostatin-28 (SRIF-28) have similar biological activities but differ in their potency. Somatostatins inhibit the release of growth hormone in contrast to Growth Hormone Factor (GRF), which stimulates the release of growth hormone. Somatostatins also inhibit the release of prolactin and thyrotropin, peptide hormones from the pituitary gland and glucagon and insulin from the pancreas. It also controls the secretion of gut hormones and functions as a neurotransmitter. 수량 카트담기 견적문의
	Spexin (36 - 49), amidated, human/mouse/rat Cat No. AS-65569 규격 1 mg 제조사 Anaspec 제품정보 Spexin is a novel peptide hormone that is derived from prohormone proNPQ and is conserved amongst mammalian species. Spexin (36-49) is post-translationally amidated with a C-terminal amidation processing signal motif (GRR) following Q49 residue of the pro-hormone. Spexin reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents. Recently it was suggested that this peptide may play a role in lipid and glucose metabolism in patients with type-2 diabetes mellitus. 수량 카트담기 견적문의
	Spexin - 2 (53 - 70), amidated, human/mouse/rat Cat No. AS-65570 규격 1 mg 제조사 Anaspec 제품정보 This is amidated Spexin-2 (53-70) peptide showing similar biological function as that of its non- amidated version (Cat # 65586) as a central modulator of cardiovascular and renal function. Spexin-2 is a novel peptide hormone that is derived from prohormone proNPQ and is conserved amongst mammalian species. 수량 카트담기 견적문의
	Spexin - 2 (53 - 70), human/mouse/rat Cat No. AS-65586 규격 1 mg 제조사 Anaspec 제품정보 This is Spexin-2 (53-70), non-amidated version of the novel peptide hormone that is derived from prohormone proNPQ and is conserved amongst mammalian species. It is a central modulator of cardiovascular and renal function. Spexin-2, when administered to rats, decreases heart rate and increases urine flow rate 수량 카트담기 견적문의
	Trp Cage Cat No. AS-62072 규격 1 mg 제조사 Anaspec 제품정보 This peptide is a C-terminal fragment of exendin-4. This 20-residue construct is over 95% folded in water at physiological pH, and exhibits a tightly folded tertiary structure in solution. Trp Cage is a highly stable mini-protein fold. It consists of a short helix, a 3,10 helix and a C-terminal poly-proline that packs against a Trp in the alpha helix. It is known to fold within 4 nanoseconds. This stable fast-folding Trp Cage sequence displays special stabilizing features specific to this miniprotein. 수량 카트담기 견적문의

관련제품

	Cat No.	품명	규격	제조사	제품정보	수량	견적문의
	AS-72209	SensoLyte ® 520 Enterokinase Activity Assay Kit *Fluorimetric*	1 kit	Anaspec	The SensoLyte® 520 Enterokinase Assay Kit is optimized for detecting activity of enterokinase. This kit employs a novel internally quenched 5-FAM/QXL FRET substrate for enterokinase. Enterokinase cleaves the FRET substrate into two separate fragments resulting in release of 5-FAM fluorescence which can be monitored at excitation/emission= 490/520 nm. The long wavelength fluorescence of 5-FAM is less interfered by the autofluorescence of components in biological samples and test compounds. The assay can detect as low as 1.25 ng/mL of active enterokinase. Kit size: 100 assays		카트담기 견적문의
	AS-72231	SensoLyte ® 520 IDE Activity Assay Kit *Fluorimetric*	1 kit	Anaspec	The SensoLyte® 520 IDE Activity Assay Kit can be used to detect enzyme activity in biological samples or in purified enzyme preparations. The unique FRET substrate was derived from an APP sequence designed to reduce cross reactivity with Neprilysin, ADAM10, TACE, BACE-1, and BACE-2. When active IDE cleaves the FRET substrate, it results in an increase of 5-FAM fluorescence, which is monitored at excitation/emission = 490 nm/520 nm. The long wavelength fluorescence of 5-FAM is also less interfered by the autofluorescence of components in biological samples and test compounds. This assay can detect as low as 0.8 ng/mL active IDE.		카트담기 견적문의
	AS-72223	SensoLyte ® 520 Neprilysin Activity Assay Kit *Fluorimetric*	1 kit	Anaspec	The SensoLyte® 520 Neprilysin Assay Kit employs a novel internally quenched 5-FAM/QXL® FRET substrate for the detection of neprilysin activity. The enzyme cleaves the FRET substrate into two separate fragments resulting in the release of 5-FAM fluorescence, which can be monitored at excitation /emission= 490/520 nm. The long wavelength fluorescence of 5-FAM is less interfered by the autofluorescence of components in biological samples and test compounds. The assay can detect as low as 0.78 ng/mL of active Neprilysin.		카트담기 견적문의
	AS-72197	SensoLyte ® AMC DPPIV Assay Kit *Fluorimetric*	1 kit	Anaspec	The SensoLyte® AMC DPPIV Assay Kit provides a convenient method for high throughput screening (HTS) of DPPIV inhibitors and for continuous assay of DPPIV activity using a fluorogenic substrate that has a high reactivity and low background. DPPIV cleaves the substrate resulting in release of AMC (7-amino-4-methylcoumarin) fluorophore. Fluorescence can be monitored at excitation /emission= 354/442 nm. This kit can be used for high throughput screening of DPPIV inhibitors.		카트담기 견적문의
	AS-72196	SensoLyte ® Rh110 DPPIV Assay Kit *Fluorimetric*	1 kit	Anaspec	The SensoLyte® Rh110 DPPIV Assay Kit provides a convenient method for high throughput screening of DPPIV inhibitors and for continuous assay of DPPIV activity utilizing a fluorogenic peptide. Upon enzyme cleavage, the peptide releases the Rh110 fluorophore with bright green fluorescence that can be detected at Ex/Em=490/520 nm. The longer-wavelength spectra and higher extinction coefficient of the Rh110 provide greater sensitivity and less interference from reaction components.		카트담기 견적문의
	AS-72210	SensoLyte ® Rh110 Enterokinase Activity Assay Kit *Fluorimetric*	1 kit	Anaspec	The SensoLyte® Rh110 Enterokinase Assay Kit is optimized for detection of enterokinase activity using a fluorogenic substrate. Upon enzyme cleavage, this substrate generates the Rh110 (rhodamine 110) fluorophore with bright green fluorescence that can be detected at excitation/emission=490/520 nm. The longer-wavelength spectra and higher extinction coefficient of the Rh110 provide greater sensitivity and less interference from other reaction components. The assay can detect as low as 0.31 ng/mL active enterokinase. Kit size: 100 assays		카트담기 견적문의

	전체선택
	SensoLyte ® 520 Enterokinase Activity Assay Kit *Fluorimetric* Cat No. AS-72209 규격 1 kit 제조사 Anaspec 제품정보 The SensoLyte® 520 Enterokinase Assay Kit is optimized for detecting activity of enterokinase. This kit employs a novel internally quenched 5-FAM/QXL FRET substrate for enterokinase. Enterokinase cleaves the FRET substrate into two separate fragments resulting in release of 5-FAM fluorescence which can be monitored at excitation/emission= 490/520 nm. The long wavelength fluorescence of 5-FAM is less interfered by the autofluorescence of components in biological samples and test compounds. The assay can detect as low as 1.25 ng/mL of active enterokinase. Kit size: 100 assays 수량 카트담기 견적문의
	SensoLyte ® 520 IDE Activity Assay Kit *Fluorimetric* Cat No. AS-72231 규격 1 kit 제조사 Anaspec 제품정보 The SensoLyte® 520 IDE Activity Assay Kit can be used to detect enzyme activity in biological samples or in purified enzyme preparations. The unique FRET substrate was derived from an APP sequence designed to reduce cross reactivity with Neprilysin, ADAM10, TACE, BACE-1, and BACE-2. When active IDE cleaves the FRET substrate, it results in an increase of 5-FAM fluorescence, which is monitored at excitation/emission = 490 nm/520 nm. The long wavelength fluorescence of 5-FAM is also less interfered by the autofluorescence of components in biological samples and test compounds. This assay can detect as low as 0.8 ng/mL active IDE. 수량 카트담기 견적문의
	SensoLyte ® 520 Neprilysin Activity Assay Kit *Fluorimetric* Cat No. AS-72223 규격 1 kit 제조사 Anaspec 제품정보 The SensoLyte® 520 Neprilysin Assay Kit employs a novel internally quenched 5-FAM/QXL® FRET substrate for the detection of neprilysin activity. The enzyme cleaves the FRET substrate into two separate fragments resulting in the release of 5-FAM fluorescence, which can be monitored at excitation /emission= 490/520 nm. The long wavelength fluorescence of 5-FAM is less interfered by the autofluorescence of components in biological samples and test compounds. The assay can detect as low as 0.78 ng/mL of active Neprilysin. 수량 카트담기 견적문의
	SensoLyte ® AMC DPPIV Assay Kit *Fluorimetric* Cat No. AS-72197 규격 1 kit 제조사 Anaspec 제품정보 The SensoLyte® AMC DPPIV Assay Kit provides a convenient method for high throughput screening (HTS) of DPPIV inhibitors and for continuous assay of DPPIV activity using a fluorogenic substrate that has a high reactivity and low background. DPPIV cleaves the substrate resulting in release of AMC (7-amino-4-methylcoumarin) fluorophore. Fluorescence can be monitored at excitation /emission= 354/442 nm. This kit can be used for high throughput screening of DPPIV inhibitors. 수량 카트담기 견적문의
	SensoLyte ® Rh110 DPPIV Assay Kit *Fluorimetric* Cat No. AS-72196 규격 1 kit 제조사 Anaspec 제품정보 The SensoLyte® Rh110 DPPIV Assay Kit provides a convenient method for high throughput screening of DPPIV inhibitors and for continuous assay of DPPIV activity utilizing a fluorogenic peptide. Upon enzyme cleavage, the peptide releases the Rh110 fluorophore with bright green fluorescence that can be detected at Ex/Em=490/520 nm. The longer-wavelength spectra and higher extinction coefficient of the Rh110 provide greater sensitivity and less interference from reaction components. 수량 카트담기 견적문의
	SensoLyte ® Rh110 Enterokinase Activity Assay Kit *Fluorimetric* Cat No. AS-72210 규격 1 kit 제조사 Anaspec 제품정보 The SensoLyte® Rh110 Enterokinase Assay Kit is optimized for detection of enterokinase activity using a fluorogenic substrate. Upon enzyme cleavage, this substrate generates the Rh110 (rhodamine 110) fluorophore with bright green fluorescence that can be detected at excitation/emission=490/520 nm. The longer-wavelength spectra and higher extinction coefficient of the Rh110 provide greater sensitivity and less interference from other reaction components. The assay can detect as low as 0.31 ng/mL active enterokinase. Kit size: 100 assays 수량 카트담기 견적문의

최근 본 제품